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8 Article(s) on File
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Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Mavrakis KJ,
Wolfe AL,
Oricchio E,
Palomero T,
de Keersmaecker K,
McJunkin K,
Zuber J,
James T,
Chang K,
Khan AA,
Leslie CS,
Parker JS,
Paddison PJ,
Tam W,
Ferrando A,
Wendel HG

Nature Cell Biology
  12 (4): 372-U159; Apr 2010   PMCID: PMC2989719
[Abstract]
[DOI] [Full Text] [PDF]

Tumorigenic activity and therapeutic inhibition of Rheb GTPase
Mavrakis KJ,
Zhu H,
Silva RL,
Mills JR,
Teruya-Feldstein J,
Lowe SW,
Tam W,
Pelletier J,
Wendel HG

Genes Dev
  22 (16): 2178-88; Aug 15 2008   PMCID: PMC2518821
[Abstract]
[DOI] [Full Text]

mTORC1 promotes survival through translational control of Mcl-1
Mills JR,
Hippo Y,
Robert F,
Chen SM,
Malina A,
Lin CJ,
Trojahn U,
Wendel HG,
Charest A,
Bronson RT,
Kogan SC,
Nadon R,
Housman DE,
Lowe SW,
Pelletier J

Proc Natl Acad Sci U S A
  105 (31): 10853-10858; Aug 5 2008   PMCID: PMC2504845
[Abstract]
[DOI] [Full Text] [PDF]

Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model
Bordeleau ME,
Robert F,
Gerard B,
Lindqvist L,
Chen SM,
Wendel HG,
Brem B,
Greger H,
Lowe SW,
Porco JA,
Pelletier J

J Clin Invest
  118 (7): 2651- 2660; Jul 1 2008   PMCID: PMC2423864
[Abstract]
[DOI] [Full Text] [PDF]

Dissecting eIF4E action in tumorigenesis
Wendel HG,
Silva RL,
Malina A,
Mills JR,
Zhu H,
Ueda T,
Watanabe-Fukunaga R,
Fukunaga R,
Teruya-Feldstein J,
Pelletier J,
Lowe SW

Genes Dev
  21 (24): 3232-7; Dec 15 2007   PMCID: PMC2113024
[Abstract]
[DOI] [Full Text] [PDF]

Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils
Martinelli S,
Kostylina G,
Niggli V,
Baumann C,
Fey MF,
Wendel HG,
Lowe SW,
Yousefi S,
Simon HU

Oncogene
  25 (52): 6915-6923; 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Reversing drug resistance in vivo
Wendel HG,
Lowe SW

Cell Cycle
  3 (7): 847-9; Jul 2004  
[Abstract]
[Full Text]

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
Wendel HG,
De Stanchina E,
Fridman JS,
Malina A,
Ray S,
Kogan S,
Cordon-Cardo C,
Pelletier J,
Lowe SW

Nature
  428 (6980): 332-7; Mar 18 2004  
[Abstract]
[DOI] [Full Text]


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