Cold Spring Harbor Library  CSHL: Home
   Home       Services       Archives       About Us   
 
CSHL Publication List
CSHL Authors Publications
Go back to Search Mode

          
Sort by   in order
37 Article(s) on File
Page 1 of 1
Gain-of-function mutations in chromatin regulators as a tumorigenic mechanism and opportunity for therapeutic intervention
Shen C,
Vakoc CR

Current Opinion in Oncology
  27 (1): 57-63; Nov 14 2014   Nlm
[Abstract]
[DOI] [Full Text]

Brd4 is on the move during inflammation
Xu Y,
Vakoc CR

Trends in Cell Biology
  (0): Oct 3 2014   NLM
[Abstract]
[DOI] [Full Text]

The mechanisms behind the therapeutic activity of BET bromodomain inhibition
Shi J,
Vakoc CR

Mol Cell
  54 (5): 728-36; Jun 5 2014   Nlm
[Abstract]
[DOI] [Full Text]

THE EPIGENETIC READER BRD4 SERVES AS A NOVEL MARKER AND TARGET IN AGGRESSIVE SYSTEMIC MASTOCYTOSIS AND MAST CELL LEUKEMIA
Wedeh G,
Cerny-Reiterer S,
Hadzijusufovic E,
Herrmann H,
Blatt K,
Eisenwort G,
Hoermann G,
Sperr WR,
Muellauer L,
Vakoc CR,
Bradner JE,
Horny H,
Zuber J,
Arock M,
Valent P

Haematologica
  99 (0): 514-515; Jun 2014   ThomsonReuters
[Full Text]

A rationale to target the SWI/SNF complex for cancer therapy
Hohmann AF,
Vakoc CR

Trends in Genetics
  30 (8): 356-363; Jun 2014 2014   NLM
[Abstract]
[DOI] [Full Text]

A Chromatin-Dependent Role of the Fragile X Mental Retardation Protein FMRP in the DNA Damage Response
Alpatov R,
Lesch BJ,
Nakamoto-Kinoshita M,
Blanco A,
Chen S,
Stutzer A,
Armache KJ,
Simon MD,
Xu C,
Ali M,
Murn J,
Prisic S,
Kutateladze TG,
Vakoc CR,
Min J,
Kingston RE,
Fischle W,
Warren ST,
Page DC,
Shi Y

Cell
  157 (4): 869-81; May 8 2014   NLM
[Abstract]
[DOI] [Full Text]

MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia
Chen C,
Liu Y,
Rappaport AR,
Kitzing T,
Schultz N,
Zhao Z,
Shroff AS,
Dickins RA,
Vakoc CR,
Bradner JE,
Stock W,
LeBeau MM,
Shannon KM,
Kogan S,
Zuber J,
Lowe SW

Cancer Cell
  25 (5): 652-65; May 1 2014   Nlm
[Abstract]
[DOI] [Full Text]

MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
Chen C,
Liu Y,
Rappaport AR,
Kitzing T,
Schultz N,
Zhao Z,
Shroff AS,
Dickins RA,
Vakoc CR,
Bradner JE,
Stock W,
Lebeau MM,
Shannon KM,
Kogan S,
Zuber J,
Lowe SW

Cancer Cell
  25 (5): 652-665; Apr 30 2014   NLM
[Abstract]
[DOI] [Full Text]

Cancer therapy resistance: chasing epigenetics
Vakoc CR,
Garcia-Manero G,
Look AT

Nature Medicine
  20 (4): 340-341; Apr 2014  
[Abstract]
[DOI] [Full Text]

A new bump in the epigenetic landscape
Bhagwat AS,
Vakoc CR

Molecular Cell
  53 (6): 857-8; Mar 20 2014   Nlm
[Abstract]
[DOI] [Full Text]

C/EBPalpha: critical at the origin of leukemic transformation
Roe JS,
Vakoc CR

J Exp Med
  211 (1): 1-4; Jan 13 2014   Nlm
[Abstract]
[DOI] [Full Text]

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
Shi J,
Whyte WA,
Zepeda-Mendoza CJ,
Milazzo JP,
Shen C,
Roe JS,
Minder JL,
Mercan F,
Wang E,
Eckersley-Maslin MA,
Campbell AE,
Kawaoka S,
Shareef S,
Zhu Z,
Kendall J,
Muhar M,
Haslinger C,
Yu M,
Roeder RG,
Wigler MA,
Blobel GA,
Zuber J,
Spector DL,
Young RA,
Vakoc CR

Genes Dev
  27 (24): 264-273 ; Nov 27 2013   NLM
[Abstract]
[DOI] [Full Text]

Oncogene interference through targeting of chromatin regulators
Roe JS,
Vakoc CR

Cell Cycle
  12 (10): 1475-1476; May 15 2013   Nlm
[DOI] [Full Text]

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia
Wang E,
Kawaoka S,
Yu M,
Shi J,
Ni T,
Yang W,
Zhu J,
Roeder RG,
Vakoc CR

Proc Natl Acad Sci U S A
  110 (10): 3901-6; Mar 5 2013   Nlm
[Abstract]
[DOI] [Full Text]

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia
Shi J,
Wang E,
Zuber J,
Rappaport A,
Taylor M,
Johns C,
Lowe SW,
Vakoc CR

Oncogene
  32 (7): 930-938; Feb 2 2013   NLM
[Abstract]
[DOI] [Full Text]

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia (AML)
Herrmann H,
Blatt K,
Shi J,
Gleixner KV,
Cerny-Reiterer S,
Müllauer L,
Vakoc CR,
Sperr WR,
Horny HP,
Bradner JE,
Zuber J,
Valent P

Oncotarget
  3 (12): 1588-1599; Dec 2012  
[Abstract]
[Full Text]

WRAD: enabler of the SET1-family of H3K4 methyltransferases
Ernst P,
Vakoc CR

Briefings in Functional Genomics
  11 (3): 217-226; May 2012  
[Abstract]
[DOI] [Full Text]

Inhibition of c-Myc Expression and Function in Hematologic Malignancies
Issa GC,
Delmore JE,
McKeown MR,
Lemieux ME,
Rahl PB,
Jacobs HM,
Kastritis E,
Gilpatrick T,
Paranal RM,
Qi J,
Shi JW,
Chesi M,
Schinzel AC,
Vakoc CR,
Bergsagel PL,
Richardson PG,
Young R,
Hahn WC,
Ghobrial IM,
Anderson KC,
Kung AL,
Mitsiades CS,
Bradner JE

Blood
  118 (21): 613-614; Nov 2011  
[Full Text]

Small-Molecule Inhibition of BRD4 Is a Novel Promising Approach to Therapeutically Target Leukemia Stem Cells in AML
Herrmann H,
Blatt K,
Shi JW,
Rappaport AR,
Gleixner KV,
Cerny-Reiterer S,
Peter B,
Wang E,
Sperr WR,
Bradner JE,
Lowe SW,
Vakoc CR,
Zuber J,
Valent P

Blood
  118 (21): 1487-1487; Nov 2011  
[Full Text]

BET bromodomain inhibition as a therapeutic strategy to target c-Myc
Delmore JE,
Issa GC,
Lemieux ME,
Rahl PB,
Shi J,
Jacobs HM,
Kastritis E,
Gilpatrick T,
Paranal RM,
Qi J,
Chesi M,
Schinzel AC,
McKeown MR,
Heffernan TP,
Vakoc CR,
Bergsagel PL,
Ghobrial IM,
Richardson PG,
Young RA,
Hahn WC,
Anderson KC,
Kung AL,
Bradner JE,
Mitsiades CS

Cell
  146 (6): 904-917; Sep 16 2011   PMC3187920
[Abstract]
[DOI] [Full Text]

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Zuber J,
Shi J,
Wang E,
Rappaport AR,
Herrmann H,
Sison EA,
Magoon D,
Qi J,
Blatt K,
Wunderlich M,
Taylor MJ,
Johns C,
Chicas A,
Mulloy JC,
Kogan SC,
Brown P,
Valent P,
Bradner JE,
Lowe SW,
Vakoc CR

Nature
  478 (7370): 524-528; Aug 3 2011   NLM
[Abstract]
[DOI]

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
Zuber J,
Rappaport AR,
Luo W,
Wang E,
Chen C,
Vaseva AV,
Shi J,
Weissmueller S,
Fellman C,
Taylor MJ,
Weissenboeck M,
Graeber TG,
Kogan SC,
Vakoc CR,
Lowe SW

Genes Dev
  25 (15): 1628-1640; Aug 1 2011  
[Abstract]
[DOI]

An RNA1 Screen Reveals a Pattern of Addiction to Epigenetic Pathways That Distinguishes MLL AF9 Leukemia From Normal Hematopoietic Cells
Vakoc CR,
Zuber J,
Lowe S,
Wang E,
Rappaport AR,
Shi JW

Blood
  116 (21): 35-35; Nov 2010   ISI


PAF Is in the Cabal of MLL1-Interacting Proteins that Promote Leukemia
Speck NA,
Vakoc CR

Cancer Cell
  17 (6): 531-532; Jun 15 2010  
[Abstract]
[DOI] [Full Text] [PDF]

A Reconfigured Pattern of MLL Occupancy within Mitotic Chromatin Promotes Rapid Transcriptional Reactivation Following Mitotic Exit
Blobel GA,
Kadauke S,
Wang E,
Lau AW,
Zuber J,
Chou MM,
Vakoc CR

Molecular Cell
  36 (6): 970-983; Dec 24 2009   PMC2818742
[Abstract]
[DOI] [Full Text]

Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate
Chou ST,
Khandros E,
Bailey LC,
Nichols KE,
Vakoc CR,
Yao Y,
Huang ZJ,
Crispino JD,
Hardison RC,
Blobel GA,
Weiss MJ

Blood
  114 (5): 983-994; Jul 30 2009   PMC2721792
[Abstract]
[DOI] [Full Text] [PDF]

Low frequency of MLL3 mutations in colorectal carcinoma
Vakoc CR,
Blobel GA,
Wen Y,
Gibbs RA,
Johnstone CN,
Rustgi AK

Cancer Genetics and Cytogenetics
  189 (2): 140-141; Mar 2009  
[DOI] [Full Text] [PDF]

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
Tripic T,
Deng W,
Cheng Y,
Zhang Y,
Vakoc CR,
Gregory GD,
Hardison RC,
Blobel GA

Blood
  113 (10): 2191-2201; 2009  
[Abstract]
[DOI] [Full Text]

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells
Steger DJ,
Lefterova MI,
Ying L,
Stonestrom AJ,
Schupp M,
Zhuo D,
Vakoc AL,
Kim JE,
Chen J,
Lazar MA,
Blobel GA,
Vakoc CR

Molecular and Cellular Biology
  28 (8): 2825-2839; 2008  
[Abstract]
[DOI] [Full Text]

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus
Jing H,
Vakoc CR,
Ying L,
Mandat S,
Wang H,
Zheng X,
Blobel GA

Molecular Cell
  29 (2): 232-242; 2008  
[Abstract]
[DOI] [Full Text]

Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes
Gregory GD,
Vakoc CR,
Rozovskaia T,
Zheng X,
Patel S,
Nakamura T,
Canaani E,
Blobel GA

Molecular and Cellular Biology
  27 (24): 8466-8479; 2007  
[Abstract]
[DOI] [Full Text]

Acetylation of GATA-1 is required for chromatin occupancy
Lamonica JM,
Vakoc CR,
Blobel GA

Blood
  108 (12): 3736-3738; 2006  
[Abstract]
[DOI] [Full Text]

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation
Zeng PY,
Vakoc CR,
Chen ZC,
Blobel GA,
Berger SL

Biotechniques
  41 (6): 694-698; 2006  
[DOI] [Full Text]

FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1
Hong W,
Nakazawa M,
Chen YY,
Kori R,
Vakoc CR,
Rakowski C,
Blobel GA

Embo Journal
  24 (13): 2367-2378; 2005  
[Abstract]
[DOI] [Full Text]

Histone H3 lysine 9 methylation and HP1γ are associated with transcription elongation through mammalian chromatin
Vakoc CR,
Mandat SA,
Olenchock BA,
Blobel GA

Molecular Cell
  19 (3): 381-391; 2005  
[Abstract]
[DOI] [Full Text]

Proximity among distant regulatory elements at the beta globin locus requires GATA-1 and FOG-1
Vakoc CR,
Letting DL,
Gheldof N,
Sawado T,
Bender MA,
Groudine M,
Weiss MJ,
Dekker J,
Blobel GA

Molecular Cell
  17 (3): 453-462; 2005  
[Abstract]
[DOI] [Full Text]

Global regulation of erythroid gene expression by transcription factor GATA-1
Welch JJ,
Watts JA,
Vakoc CR,
Yao Y,
Wang H,
Hardison RC,
Blobel GA,
Chodosh LA,
Weiss MJ

Blood
  104 (10): 3136-3147; 2004  
[Abstract]
[DOI] [Full Text]


Page 1 of 1

Go back to Search Mode


Last Updated: November, 2017
Most Recent Publications: Jan 13, 2015

© 2012   CSHL Library and Archives   1 Bungtown Rd.   Cold Spring Harbor, NY 11724   Library Information 516-367-6872
CSHL Home Intranet