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14 Article(s) on File
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Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
Bywater M,
Poortinga G,
Sanij E,
Hein N,
Peck A,
Cullinane C,
Wall M,
Cluse L,
Drygin D,
Anderes K,
Huser N,
Proffitt C,
Bliesath J,
Haddach M,
Schwaebe M,
Ryckman DM,
Rice W,
Schmitt C,
Lowe S,
Johnstone R,
Pearson R,
McArthur G,
Hannan R

Cancer Cell
  22 (1): 51-65; Jul 15 2012  
[Abstract]
[DOI] [Full Text]

Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo
Helmrich A,
Lee S,
OBrien P,
Dorken B,
Lowe SW,
Schrock E,
Schmitt CA

Oncogene
  24 (26): 4174-4182; Jun 2005  
[Abstract]
[DOI] [Full Text] [PDF]

Impact of recurrent cytogenetic abnormalities in INK4a/ARF defective primary lymphomas on chemosensitivity in vivo
Schmitt CA,
Helmrich A,
Lee S,
Dorken B,
Lowe SW,
Schrock E

Blood
  102 (11): 68A-69A; Nov 2003  
[Full Text]

A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy
Schmitt CA,
Fridman JS,
Yang M,
Lee S,
Baranov E,
Hoffman RM,
Lowe SW

Cell
  109 (3): 335-346; May 2002  
[Full Text]

Dissecting p53 tumor suppressor functions in vivo
Schmitt CA,
Fridman JS,
Yang M,
Baranov E,
Hoffman RM,
Lowe SW

Cancer Cell
  1 (3): 289-298; Apr 2002  
[Full Text]

Genetics of drug sensitivity and resistance in a mouse lymphoma model
Lowe SW,
Schmitt C,
Fridman J,
Rosenthal C

Clinical Cancer Research
  7 (11): 3828S-3829S; Nov 2001  
[Full Text]

Myc-driven lymphomas respond with both apoptosis and senescence to anticancer treatment in vivo
Schmitt CA,
Yang M,
Fridman JS,
Baranov E,
Hoffman RM,
Lowe SW

Blood
  98 (11): 172B-172B; Nov 2001  
[Full Text]

Apoptosis is critical for drug response in vivo
Schmitt CA,
Lowe SW

Drug Resistance Updates
  4 (2): 132-134; Apr 2001  
[Full Text]

Bcl-2 mediates chemoresistance in matched pairs of primary E mu-myc lymphomas in vivo
Schmitt CA,
Lowe SW

Blood Cells Molecules and Diseases
  27 (1): 206-216; Jan 2001  
[Abstract]
[DOI] [Full Text]

Genetic analysis of chemoresistance in primary murine lymphomas
Schmitt CA,
Rosenthal CT,
Lowe SW

Nature Medicine
  6 (9): 1029-1035; Sep 2000  
[Abstract]
[Full Text]

Molecular genetics of drug sensitivity and resistance in a mouse lymphoma model
Schmitt CA,
Fridman J,
Lowe SW

British Journal of Cancer
  83 (0): 4-4; Jul 2000  


DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model
Schmitt CA,
Wallace-Brodeur RR,
Rosenthal CT,
McCurrach ME,
Lowe SW

Cold Spring Harbor Symposia on Quantitative Biology
  65 (0): 499-510; 2000  
[Full Text]

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
Schmitt CA,
McCurrach ME,
de Stanchina E,
Wallace-Brodeur RR,
Lowe SW

Genes Dev
  13 (20): 2670-7; Oct 15 1999  
[Abstract]
[Full Text]

Apoptosis and therapy
Schmitt CA,
Lowe SW

J Pathol
  187 (1): 127-37; Jan 1999  
[Abstract]
[Full Text]


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