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30 Article(s) on File
Page 1 of 1
The contribution of de novo coding mutations to autism spectrum disorder
Iossifov I,
ORoak BJ,
Sanders SJ,
Ronemus M,
Krumm N,
Levy D,
Stessman HA,
Witherspoon KT,
Vives L,
Patterson KE,
Smith JD,
Paeper B,
Nickerson DA,
Dea J,
Dong S,
Gonzalez LE,
Mandell JD,
Mane SM,
Murtha MT,
Sullivan CA,
Walker MF,
Waqar Z,
Wei L,
Willsey AJ,
Yamrom B,
Lee YH,
Grabowska E,
Dalkic E,
Wang Z,
Marks S,
Andrews P,
Leotta A,
Kendall J,
Hakker I,
Rosenbaum J,
Ma B,
Rodgers L,
Troge J,
Narzisi G,
Yoon S,
Schatz MC,
Ye K,
McCombie WR,
Shendure J,
Eichler EE,
State MW,
Wigler M

Nature
  515 (7526): 2160-U136; Nov 13 2014   NLM
[Abstract]
[DOI] [Full Text]

Genome-wide copy number analysis of single cells
Baslan T,
Kendall JT,
Rodgers L,
Cox H,
Riggs M,
Stepansky A,
Troge JE,
Ravi K,
Esposito D,
Lakshmi B,
Wigler M,
Navin NE,
Hicks JB

Nat Protoc
  7 (6): 1024-41; May 3 2012   Nlm
[Abstract]
[DOI] [Full Text]

De novo gene disruptions in children on the autistic spectrum
Iossifov I,
Ronemus M,
Levy D,
Wang Z,
Hakker I,
Rosenbaum J,
Yamrom B,
Lee YH,
Narzisi G,
Leotta A,
Kendall J,
Grabowska E,
Ma B,
Marks S,
Rodgers L,
Stepansky A,
Troge J,
Andrews P,
Bekritsky M,
Pradhan K,
Ghiban E,
Kramer M,
Parla J,
Demeter R,
Fulton LL,
Fulton RS,
Magrini VJ,
Ye K,
Darnell JC,
Darnell RB,
Mardis ER,
Wilson RK,
Schatz MC,
McCombie WR,
Wigler M

Neuron
  74 (2): 285-99; Apr 26 2012   Nlm
[Abstract]
[DOI] [Full Text]

Inferring tumor progression from genomic heterogeneity
Navin NE,
Krasnitz A,
Rodgers L,
Cook K,
Meth JL,
Kendall JT,
Riggs M,
Eberling Y,
Troge JE,
Grubor V,
Levy D,
Lundin P,
Månér S,
Zetterberg A,
Hicks JB,
Wigler MH

Genome Research
  20 (1): 68-80; Jan 2010   PMCID: PMC2798832
[Abstract]
[DOI] [Full Text] [PDF]

Identification of alterations in DNA copy number in host stromal cells during tumor progression
Pelham RJ,
Rodgers L,
Hall IM,
Lucito R,
Nguyen KC,
Navin NE,
Hicks JB,
Mu D,
Powers S,
Wigler MH,
Botstein D

Proc Natl Acad Sci U S A
  103 (52): 19848-19853; Dec 2006  
[Abstract]
[DOI] [Full Text]

Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation
Lucito R,
Healy J,
Alexander J,
Reiner A,
Esposito D,
Chi MY,
Rodgers L,
Brady A,
Sebat J,
Troge JE,
West JA,
Rostan S,
Nguyen KC,
Powers S,
Ye KQ,
Olshen A,
Venkatraman E,
Norton L,
Wigler MH

Genome Research
  13 (10): 2291-2305; Oct 2003  
[Abstract]
[DOI] [Full Text]

DBC2, a candidate for a tumor suppressor gene involved in breast cancer
Hamaguchi M,
Meth JL,
von Klitzing C,
Wei W,
Esposito D,
Rodgers L,
Walsh T,
Welcsh P,
King MC,
Wigler MH

Proceedings of the National Academy of Sciences of the United States of America
  99 (21): 13647-13652; Oct 2002  
[Full Text]

Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor
Stolarov J,
Chang K,
Reiner A,
Rodgers L,
Hannon GJ,
Wigler MH,
Mittal V

Proceedings of the National Academy of Sciences of the United States of America
  98 (23): 13043-13048; Nov 2001  
[Abstract]
[DOI] [Full Text]

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
Li J,
Yen C,
Liaw D,
Podsypanina K,
Bose S,
Wang SI,
Puc J,
Miliaresis C,
Rodgers L,
McCombie R,
Bigner SH,
Giovanella BC,
Ittmann M,
Tycko B,
Hibshoosh H,
Wigler MH,
Parsons R

Science
  275 (5308): 1943-7; Mar 28 1997  
[Abstract]
[DOI] [Full Text]

Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases
Bolger GB,
Rodgers L,
Riggs M

Gene
  149 (2): 237-44; Nov 18 1994  
[Abstract]
[DOI] [Full Text]

A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs
Bolger G,
Michaeli T,
Martins T,
St John T,
Steiner B,
Rodgers L,
Riggs M,
Wigler MH,
Ferguson K

Mol Cell Biol
  13 (10): 6558-71; Oct 1993  
[Abstract]
[Full Text]

Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase- deficient Saccharomyces cerevisiae
Michaeli T,
Bloom TJ,
Martins T,
Loughney K,
Ferguson K,
Riggs M,
Rodgers L,
Beavo JA,
Wigler MH

Journal of Biological Chemistry
  268 (17): 12925-12932; Jun 1993  
[Abstract]
[Full Text]

A gene encoding a protein with seven zinc finger domains acts on the sexual differentiation pathways of Schizosaccharomyces pombe
Xu HP,
Rajavashisth T,
Grewal N,
Jung V,
Riggs M,
Rodgers L,
Wigler MH

Mol Biol Cell
  3 (7): 721-34; Jul 1992  
[Abstract]
[Full Text]

Snc1, a Yeast Homolog of the Synaptic Vesicle-Associated Membrane-Protein Synaptobrevin Gene Family - Genetic Interactions with the Ras and Cap Genes
Gerst JE,
Rodgers L,
Riggs M,
Wigler MH

Proceedings of the National Academy of Sciences of the United States of America
  89 (10): 4338-4342; May 1992  
[Abstract]
[Full Text]

Genetic and Biochemical-Analysis of the Adenylyl Cyclase-Associated Protein, Cap, in Schizosaccharomyces-Pombe
Kawamukai M,
Gerst J,
Field J,
Riggs M,
Rodgers L,
Wigler MH,
Young D

Molecular Biology of the Cell
  3 (2): 167-180; Feb 1992  
[Abstract]
[Full Text]

byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype
Wang Y,
Xu HP,
Riggs M,
Rodgers L,
Wigler MH

Molecular Cellular Biology
  11 (7): 3554-63; Jul 1991  
[Abstract]
[Full Text] [PDF]

Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae
Colicelli J,
Nicolette C,
Birchmeier C,
Rodgers L,
Riggs M,
Wigler MH

Proc Natl Acad Sci U S A
  88 (7): 2913-7; Apr 1 1991  
[Abstract]
[DOI] [Full Text] [PDF]

sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1
Wang Y,
Boguski M,
Riggs M,
Rodgers L,
Wigler M

Cell Regulation
  2 (6): 453-465; 1991  
[Abstract]
[Full Text]

Biological-Activity of the Mammalian Rap Genes in Yeast
Xu HP,
Wang Y,
Riggs M,
Rodgers L,
Wigler MH

Cell Regulation
  1 (10): 763-769; Sep 1990  
[Full Text] [PDF]

Cloning and characterization of CAP , the Saccharomyces cerevisiae gene encoding the 70 kDa adenylyl cyclase associated protein.
Field J,
Vojtek A,
Ballester R,
Bolger G,
Colicelli J,
Ferguson K,
Gerst J,
Kataoka T,
Michaeli T,
Powers S,
Riggs M,
Rodgers L,
Wieland I,
Wheland B,
Wigler MH

Cell
  61 (2): 319-327; Apr 1990  
[DOI] [Full Text]

A gene from Schizosaccharomyces-Pombe with homology to Escherichia-Coli RNAse III blocks conjugation and sporulation when overexpressed in wild type cells
Xu HP,
Riggs M,
Rodgers L,
Wigler MH

Nucleic Acids Research
  18 (17): 5304; 1990  
[DOI] [Full Text]

Isolation of Chinese-Hamster Ovary Cell-Lines Temperature Conditional for the Cell-Surface Expression of Integral Membrane-Glycoproteins
Hearing J,
Hunter E,
Rodgers L,
Gething MJ,
Sambrook J

Journal of Cell Biology
  108 (2): 339-353; Feb 1989  
[Full Text]

Chromosomes of Older Humans Are More Prone to Aminopterine-Induced Breakage
Esposito D,
Fassina G,
Szabo P,
Deangelis P,
Rodgers L,
Weksler M,
Siniscalco M

Proceedings of the National Academy of Sciences of the United States of America
  86 (4): 1302-1306; Feb 1989  
[Full Text]

Characterization of the ros1-gene products expressed in human glioblastoma cell lines
Sharma S,
Birchmeier C,
Nikawa J,
ONeill K,
Rodgers L,
Wigler MH

Oncogene Res
  5 (2): 91-100; 1989  
[Abstract]
[Full Text]

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method
Field J,
Nikawa J,
Broek D,
MacDonald B,
Rodgers L,
Wilson IA,
Lerner RA,
Wigler MH

Molecular Cellular Biology
  8 (5): 2159-65; May 1988  
[Abstract]
[Full Text]

Fission Yeast Enters the Stationary Phase G0 State from Either Mitotic G1 or G2
Costello G,
Rodgers L,
Beach D

Current Genetics
  11 (2): 119-125; 1986  
[Full Text]

Sv40 T-Antigen and the Exocytotic Pathway
Sharma S,
Rodgers L,
Brandsma J,
Gething MJ,
Sambrook J

Embo Journal
  4 (6): 1479-1489; 1985  
[Full Text]

Lines of Bpv-Transformed Murine Cells That Constitutively Express Influenza-Virus Hemagglutinin
Sambrook J,
Rodgers L,
White J,
Gething MJ

Embo Journal
  4 (1): 91-103; 1985  
[Full Text]

Isolation of Mammalian Cell Mutants Defective in Membrane Protein Transport
Hearing J,
Bird P,
Hunter E,
Rodgers L,
Gething MJ,
Sambrook J

Journal of Cell Biology
  101 (5): 10A; 1985  


ran1+ controls the transition from mitotic division to meiosis in fission yeast
Beach D,
Rodgers L,
Gould J

Curr Genet
  10 (4): 297-311; 1985  
[Abstract]
[Full Text]


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