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14 Article(s) on File
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In Vivo RNA interference models of inducible and reversible sirt1 knockdown in kidney cells
Chuang PY,
Xu J,
Dai Y,
Jia F,
Mallipattu SK,
Yacoub R,
Gu L,
Premsrirut PK,
He JC

The American Journal of Pathology
  184 (7): 1940-56; Jul 2014   Nlm
[Abstract]
[DOI] [Full Text]

PTEN action in leukaemia dictated by the tissue microenvironment
Miething C,
Scuoppo C,
Bosbach B,
Appelmann I,
Nakitandwe J,
Ma J,
Wu G,
Lintault L,
Auer M,
Premsrirut PK,
Teruya-Feldstein J,
Hicks J,
Benveniste H,
Speicher MR,
Downing JR,
Lowe SW

Nature
  510 (7505): 402-406; May 4 2014   NLM
[Abstract]
[DOI] [Full Text]

Next Generation RNAi Mouse Models for Drug Discovery and Toxicology Assessment
Premsrirut P,
Fellmann C,
Dow L,
Lowe S,
Zuber J,
Hannon G

European Journal of Cancer
  48 (0): 16-16; Nov 6 2012  
[Full Text]

PTEN affects T-cell dissemination and survival in a murine model of T-cell lymphoma
Miething C,
Scuoppo C,
Premsrirut P,
Hicks J,
Lowe S

Onkologie
  35 (0): 6-6; Oct 2012  
[Full Text]

Proffered Paper: Next Generation RNAi Mouse Models for Drug Discovery and Toxicology Assessment
Premsrirut P,
Fellmann C,
Hannon GJ,
Lowe SW,
Zuber J,
Elledge S

European Journal of Cancer
  48 (0): S14-S14; Jul 2012  
[Full Text]

Targeting Synthetic Lethal Interactions between Myc and the eIF4F Complex Impedes Tumorigenesis
Lin CJ,
Nasr Z,
Premsrirut P,
Porco Jr J,
Hippo Y,
Lowe S,
Pelletier J

Cell Reports
  1 (4): 325-333; Apr 19 2012  
[Abstract]
[DOI] [Full Text]

A pipeline for the generation of shRNA transgenic mice
Dow LE,
Premsrirut PK,
Zuber J,
Fellmann C,
McJunkin K,
Miething C,
Park Y,
Dickins RA,
Hannon GJ,
Lowe SW

Nat Protoc
  7 (2): 374-93; Feb 2 2012   NLM
[Abstract]
[DOI] [Full Text]

Control of the senescence-associated secretory phenotype by NF-{kappa}B promotes senescence and enhances chemosensitivity
Chien Y,
Scuoppo C,
Wang X,
Fang X,
Balgley B,
Bolden JE,
Premsrirut P,
Luo W,
Chicas A,
Lee CS,
Kogan SC,
Lowe SW

Genes Dev
  25 (20): 2125-2136; Oct 15 2011   NLM
[Abstract]
[DOI]

Reversible suppression of an essential gene in adult mice using transgenic RNA interference
McJunkin K,
Mazurek A,
Premsrirut PK,
Zuber J,
Dow LE,
Simon J,
Stillman B,
Lowe SW

Proc Natl Acad Sci U S A
  108 (17): 7113-7118; Apr 26 2011   NLM PMC3084121
[Abstract]
[DOI]

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Premsrirut PK,
Dow LE,
Kim SY,
Camiolo M,
Malone CD,
Miething C,
Scuoppo C,
Zuber J,
Dickins RA,
Kogan S,
Shroyer K,
Sordella R,
Hannon GJ,
Lowe SW

Cell
  145 (1): 145-158; Mar 31 2011   Elsevier
[Abstract]
[DOI]

Transgenic, inducible RNAi in megakaryocytes and platelets in mice
Takiguchi M,
James C,
Josefsson EC,
Carmichael CL,
Premsrirut PK,
Lowe SW,
Hamilton JR,
Huang DC,
Kile BT,
Dickins RA

J Thromb Haemost
  8 (12): 2751-6; Dec 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Conditional Regulation of Tumor Suppressor Genes in Vivo Using Rna Interference
Premsrirut PK,
Miething C,
Zuber J,
Yong KS,
Hannon GJ,
Lowe SW

Journal of Investigative Medicine
  57 (3): 82; Mar 2009  
[Full Text] [PDF]

Tissue-specific and reversible RNA interference in transgenic mice
Dickins RA,
McJunkin K,
Hernando E,
Premsrirut PK,
Krizhanovsky V,
Burgess DJ,
Kim SY,
Cordon-Cardo C,
Zender L,
Hannon GJ,
Lowe SW

Nat Genet
  39 (7): 914 - 921; Jul 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Tetracycline-regulated p53 knockdown in cells and transgenic mice
Dickins RA,
Premsrirut PK,
McJunkin K,
Kim SY,
Hannon GJ,
Lowe SW

Toxicologic Pathology
  34 (7): 1006-1006; 2006  
[Full Text]


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