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16 Article(s) on File
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Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Mavrakis KJ,
Wolfe AL,
Oricchio E,
Palomero T,
de Keersmaecker K,
McJunkin K,
Zuber J,
James T,
Chang K,
Khan AA,
Leslie CS,
Parker JS,
Paddison PJ,
Tam W,
Ferrando A,
Wendel HG

Nature Cell Biology
  12 (4): 372-U159; Apr 2010   PMCID: PMC2989719
[Abstract]
[DOI] [Full Text] [PDF]

Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells
Schaniel C,
Ang YS,
Ratnakumar K,
Cormier C,
James T,
Bernstein E,
Lemischka IR,
Paddison PJ

Stem Cells
  27 (12): 2979-2991; Dec 2009  
[Abstract]
[DOI] [Full Text] [PDF]

RNA Interference
Paddison PJ,
Vogt PK

Curr Top Microbiol Immunol
  320 (0):; 2008  
[Abstract]
[Full Text]

RNA interference in mammalian cell systems
Paddison PJ

RNA Interference
  320 (0): 1-19; 2008  
[Abstract]


Wnt and TGF-ß signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
Gadue P,
Huber TL,
Paddison PJ,
Keller GM

Proceedings of the National Academy of Sciences of the United States of America
  103 (45): 16806-16811; 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Second-generation shRNA libraries covering the mouse and human genomes
Silva JM,
Li MZ,
Chang K,
Ge W,
Golding MC,
Rickles RJ,
Siolas D,
Hu G,
Paddison PJ,
Schlabach MR,
Sheth N,
Bradshaw J,
Burchard J,
Kulkarni A,
Cavet G,
Sachidanandam R,
McCombie WR,
Cleary MA,
Elledge SJ,
Hannon GJ

Nat Genet
  37 (11): 1281-8; Nov 2005  
[Abstract]
[DOI] [Full Text]

Synthetic shRNAs as potent RNAi triggers
Siolas D,
Lerner C,
Burchard J,
Ge W,
Linsley PS,
Paddison PJ,
Hannon GJ,
Cleary MA

Nat Biotechnol
  23 (2): 227-31; Feb 2005  
[Abstract]
[Full Text]

Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis
Cleary MA,
Kilian K,
Wang Y,
Bradshaw J,
Cavet G,
Ge W,
Kulkarni A,
Paddison PJ,
Chang K,
Sheth N,
Leproust E,
Coffey EM,
Burchard J,
McCombie WR,
Linsley P,
Hannon GJ

Nat Methods
  1 (3): 241-8; Dec 2004  
[Abstract]
[Full Text]

Cloning of short hairpin RNAs for gene knockdown in mammalian cells
Paddison PJ,
Cleary M,
Silva JM,
Chang K,
Sheth N,
Sachidanandam R,
Hannon GJ

Nat Methods
  1 (2): 163-7; Nov 2004  
[DOI] [Full Text]

A resource for large-scale RNA-interference-based screens in mammals
Paddison PJ,
Silva JM,
Conklin DS,
Schlabach M,
Li M,
Aruleba S,
Balija V,
OShaughnessy A,
Gnoj L,
Scobie K,
Chang K,
Westbrook T,
Cleary M,
Sachidanandam R,
McCombie WR,
Elledge SJ,
Hannon GJ

Nature
  428 (6981): 427-31; Mar 25 2004  
[Abstract]
[DOI] [Full Text]

Short hairpin activated gene silencing in mammalian cells
Paddison PJ,
Caudy AA,
Sachidanandam R,
Hannon GJ
In:
RNA Interference, Editing and Modification: methods and protocols
(ed. Gott, J. M. ) Totowa, N. J. : Humana Press; 2004. 265: 85-100  
[Abstract]
[Full Text]

siRNAs and shRNAs: Skeleton keys to the human genome
Paddison PJ,
Hannon GJ

Current Opinion in Molecular Therapeutics
  5 (3): 217-224; Jun 2003  
[Abstract]
[Full Text]

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
Hemann MT,
Fridman JS,
Zilfou JT,
Hernando E,
Paddison PJ,
Cordon-Cardo C,
Hannon GJ,
Lowe SW

Nature Genetics
  33 (3): 396-400; Mar 1 2003  
[Abstract]
[DOI] [Full Text]

RNA interference: the new somatic cell genetics?
Paddison PJ,
Hannon GJ

Cancer Cell
  2 (1): 17-23; Jul 2002  
[Full Text]

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
Paddison PJ,
Caudy AA,
Bernstein E,
Hannon GJ,
Conklin DS

Genes Development
  16 (8): 948-958; Apr 2002  
[DOI] [Full Text]

Stable suppression of gene expression by RNAi in mammalian cells
Paddison PJ,
Caudy AA,
Hannon GJ

Proceedings of the National Academy of Sciences of the United States of America
  99 (3): 1443-1448; Feb 2002  
[DOI] [Full Text]


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