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18 Article(s) on File
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Acquired Dependence of Acute Myeloid Leukemia on the DEAD-Box RNA Helicase DDX5
Mazurek A,
Park Y,
Miething C,
Wilkinson JE,
Gillis J,
Lowe S,
Vakoc C,
Stillman B

Cell Reports
  7 (6): 18887-1899; Jun 26 2014   NLM
[Abstract]
[DOI] [Full Text]

PTEN action in leukaemia dictated by the tissue microenvironment
Miething C,
Scuoppo C,
Bosbach B,
Appelmann I,
Nakitandwe J,
Ma J,
Wu G,
Lintault L,
Auer M,
Premsrirut PK,
Teruya-Feldstein J,
Hicks J,
Benveniste H,
Speicher MR,
Downing JR,
Lowe SW

Nature
  510 (7505): 402-406; May 4 2014   NLM
[Abstract]
[DOI] [Full Text]

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an E mu-myc/Bcl-2 mouse model
Mills JR,
Malina A,
Lee T,
Di Paola D,
Larsson O,
Miething C,
Grosse F,
Tang HL,
Zannis-Hadjopoulos M,
Lowe SW,
Pelletier J

Blood
  121 (17): 3402-3412; Apr 25 2013   NLM
[DOI] [Full Text]

Tumor Associated Macrophage Expression, CD163, Is Associated with Poorer Outcome in Diffuse Large B-Cell Lymphoma
Bohn OL,
Maragulia JC,
Crispin H,
Gonzalez C,
Miething C,
Zelenetz AD,
Teruya-Feldstein J

Blood
  120 (21): 1583; Nov 16 2012  
[Abstract]
[Full Text]

An oncogenome-based RNAi screen identifies a tumour suppressor network in B-cell lymphoma relying on the polyamine-hypusine axis
Miething C,
Scuoppo C,
Lindqvist L,
Reyes J,
Ruse C,
Appelmann I,
Yoon S,
Krasnitz A,
Teruya-Feldstein J,
Pappin D,
Pelletier J,
Lowe S

Onkologie
  35 (0): 104-104; Oct 6 2012  
[Full Text]

PTEN affects T-cell dissemination and survival in a murine model of T-cell lymphoma
Miething C,
Scuoppo C,
Premsrirut P,
Hicks J,
Lowe S

Onkologie
  35 (0): 6-6; Oct 2012  
[Full Text]

An RNAi-based system for loss-of-function analysis: Identification of Raf1 but not BRAF as a crucial mediator of BCR-ABL-driven leukemogenesis
Albers C,
Illert AL,
Leischner H,
Miething C,
Peschel C,
Duyster J

Onkologie
  35 (0): 170-170; Oct 2012  
[Full Text]

A tumour suppressor network relying on the polyamine-hypusine axis
Scuoppo C,
Miething C,
Lindqvist L,
Reyes J,
Ruse C,
Appelmann I,
Yoon S,
Krasnitz A,
Teruya-Feldstein J,
Pappin D,
Pelletier J,
Lowe SW

Nature
  487 (7406): 244-8; Jul 12 2012   NLM
[Abstract]
[DOI] [Full Text]

A pipeline for the generation of shRNA transgenic mice
Dow LE,
Premsrirut PK,
Zuber J,
Fellmann C,
McJunkin K,
Miething C,
Park Y,
Dickins RA,
Hannon GJ,
Lowe SW

Nat Protoc
  7 (2): 374-93; Feb 2 2012   NLM
[Abstract]
[DOI] [Full Text]

SCF(Fbxo25) suppresses B cell lymphomagenesis by targeting Hax-1 for ubiquitin mediated proteasomal degradation
Baumann U,
Targosz BS,
Lemeer S,
Nikolova V,
Kratzat S,
Fernandez-Saiz V,
Reiter C,
Rudelius M,
Miething C,
Kuster B,
Peschel C,
Keller U,
Bassermann F

Onkologie
  34 (0): 190-190; Sep 2011  
[Full Text]

An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL - Driven leukemogenesis
Albers C,
Illert AL,
Miething C,
Leischner H,
Thiede M,
Peschel C,
Duyster J

Blood
  118 (8): 2200-2210; Aug 2011  
[Abstract]
[DOI]

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Premsrirut PK,
Dow LE,
Kim SY,
Camiolo M,
Malone CD,
Miething C,
Scuoppo C,
Zuber J,
Dickins RA,
Kogan S,
Shroyer K,
Sordella R,
Hannon GJ,
Lowe SW

Cell
  145 (1): 145-158; Mar 31 2011   Elsevier
[Abstract]
[DOI]

A Single Retroviral Vector Design for the Simultaneous Expression of a Mir30 Based Shrna with An Oncogene - Identification of Raf 1 but Not BRAF as a Crucial Mediator for BCR ABL Mediated Leukemogenesis
Albers C,
Illert AL,
Leischner H,
Miething C,
Huss R,
Peschel C,
Duyster J

Blood
  116 (21): 1388-1389; Nov 2010  
[Full Text]

Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model
Bric A,
Miething C,
Bialucha CU,
Scuoppo C,
Zender L,
Krasnitz A,
Xuan Z,
Zuber J,
Wigler MH,
Hicks JB,
McCombie RW,
Hemann MT,
Hannon GJ,
Powers S,
Lowe SW

Cancer Cell
  16 (4): 324-35; Oct 6 2009   PMC2829755
[Abstract]
[DOI] [Full Text] [PDF]

Conditional Regulation of Tumor Suppressor Genes in Vivo Using Rna Interference
Premsrirut PK,
Miething C,
Zuber J,
Yong KS,
Hannon GJ,
Lowe SW

Journal of Investigative Medicine
  57 (3): 82; Mar 2009  
[Full Text] [PDF]

Senescence of activated stellate cells limits liver fibrosis
Krizhanovsky V,
Yon M,
Dickens RA,
Hearn SA,
Simon J,
Ma B,
Miething C,
Zender L,
Lowe SW

Cell
  134 (4): 657-667 ; Aug 22 2008  
[DOI] [Full Text] [PDF]

Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells
Fanta S,
Sonnenberg M,
Skorta I,
Duyster J,
Miething C,
Aulitzky WE,
van der Kuip H

Oncogene
  27 (31): 4380-4384; Jul 2008  
[Abstract]
[DOI] [Full Text] [PDF]

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Xue W,
Zender L,
Miething C,
Dickins RA,
Hernando E,
Krizhanovsky V,
Cordon-Cardo C,
Lowe SW

Nature
  445 (7128): 656-660; Feb 2007  
[Abstract]
[DOI] [Full Text] [PDF]


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