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44 Article(s) on File
Page 1 of 1
How are cohesin rings opened and closed?
Shintomi K,
Hirano T

Trends Biochem Sci
  32 (4): 154-157; Apr 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Reconstitution and subunit geometry of human condensin complexes
Onn I,
Aono N,
Hirano M,
Hirano T

Embo Journal
  26 (4): 1024-1034; 2007   PMCID: PMC1852836
[Abstract]
[DOI] [Full Text] [PDF]

Dynamic molecular linkers of the genome: the first decade of SMC proteins
Losada A,
Hirano T

Genes Development
  19 (11): 1269-1287; Jun 2005  
[Abstract]
[Full Text] [PDF]

Shugoshin protects cohesin complexes at centromeres - Discussion
Hyman T,
Watanabe Y,
Yanagida M,
Hirano T

Philosophical Transactions of the Royal Society B-Biological Sciences
  360 (1455): 521-521; Mar 2005  
[Full Text]

Cell biology - Holding sisters for repair
Hirano T

Nature
  433 (7025): 467-468; Feb 2005  
[DOI] [Full Text] [PDF]

Scc2 couples replication licensing to sister chromatid cohesion in Xenopus egg extracts
Gillespie PJ,
Hirano T

Curr Biol
  14 (17): 1598-603; Sep 7 2004  
[Abstract]
[DOI]

Visualization of early chromosome condensation: a hierarchical folding, axial glue model of chromosome structure
Kireeva N,
Lakonishok M,
Kireev I,
Hirano T,
Belmont AS

Journal of Cell Biology
  166 (6): 775-785; Sep 2004   PMCID: PMC2172117
[Abstract]
[DOI] [Full Text] [PDF]

Positive and negative regulation of SMC-DNA interactions by ATP and accessory proteins
Hirano M,
Hirano T

EMBO J
  23 (13): 2664-73; Jul 7 2004  
[Abstract]
[DOI]

Spatial and temporal regulation of Condensins I and II in mitotic chromosome assembly in human cells
Ono T,
Fang Y,
Spector DL,
Hirano T

Mol Biol Cell
  15 (7): 3296-308; Jul 2004  
[Abstract]
[Full Text] [PDF]

Real-time detection of single-molecule DNA compaction by condensin I
Strick TR,
Kawaguchi T,
Hirano T

Curr Biol
  14 (10): 874-80; May 25 2004  
[Abstract]
[DOI]

The mitotic chromosome is an assembly of rigid elastic axes organized by structural maintenance of chromosomes (SMC) proteins and surrounded by a soft chromatin envelope
Almagro S,
Riveline D,
Hirano T,
Houchmandzadeh B,
Dimitrov S

Journal of Biological Chemistry
  279 (7): 5118-5126; Feb 2004  
[Abstract]
[DOI] [Full Text]

Chromosome shaping by two condensins
Hirano T

Cell Cycle
  3 (1): 26-8; Jan 2004  
[Abstract]
[Full Text] [PDF]

Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells
Ono T,
Losada A,
Hirano M,
Myers MP,
Neuwald AF,
Hirano T

Cell
  115 (1): 109-121; Oct 2003  
[Abstract]
[DOI] [Full Text]

Individual chromosomes as viscoelastic copolymers
Almagro S,
Dimitrov S,
Hirano T,
Vallade M,
Riveline D

Europhysics Letters
  63 (6): 908-914; Sep 2003  
[Abstract]
[Full Text]

The making of the mitotic chromosome: Modern insights into classical questions
Swedlow JR,
Hirano T

Molecular Cell
  11 (3): 557-569; Mar 2003  
[Abstract]
[Full Text]

A role of topoisomerase II in linking DNA replication to chromosome condensation
Cuvier O,
Hirano T

Journal of Cell Biology
  160 (5): 645-655; Mar 2003   PMCID: PMC2173373
[Abstract]
[DOI] [Full Text] [PDF]

Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis
Losada A,
Hirano M,
Hirano T

Genes Development
  16 (23): 3004-3016; Dec 2002  
[DOI] [Full Text]

Hinge-mediated dimerization of SMC protein is essential for its dynamic interaction with DNA
Hirano M,
Hirano T

Embo Journal
  21 (21): 5733-5744; Nov 2002  
[Full Text]

SMC proteins
Gillespie PJ,
Hirano T

Current Biology
  12 (15): R513-R513; Aug 2002  
[Full Text]

Efficient supercoiling of DNA by a single condensin complex as revealed by electron spectroscopic imaging
Bazett-Jones DP,
Kimura K,
Hirano T

Molecular Cell
  9 (6): 1183-1190; Jun 2002  
[Full Text]

Distinct but overlapping domains of AKAP95 are implicated in chromosome condensation and condensin targeting
Eide T,
Carlson C,
Tasken KA,
Hirano T,
Tasken K,
Collas P

Embo Reports
  3 (5): 426-432; May 2002  
[Full Text]

The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion and repair
Hirano T

Genes Development
  16 (4): 399-414; Feb 2002  
[DOI] [Full Text]

Condensin and cohesin display different arm conformations with characteristic hinge angles
Anderson DE,
Losada A,
Erickson HP,
Hirano T

Journal of Cell Biology
  156 (3): 419-424; Feb 2002   PMCID: PMC2173330
[DOI] [Full Text] [PDF]

ISWI remodeling complexes in Xenopus egg extracts: Identification as major chromosomal components that are regulated by INCENP-aurora B
MacCallum DE,
Losada A,
Kobayashi R,
Hirano T

Molecular Biology of the Cell
  13 (1): 25-39; Jan 2002  
[DOI] [Full Text]

Chromosome cohesion and condensation in mitosis
Hirano T

Molecular Biology of the Cell
  12 (0): 131A-131A; Nov 2001  
[Full Text]

Shaping the metaphase chromosome: coordination of cohesion and condensation
Losada A,
Hirano T

Bioessays
  23 (10): 924-935; Oct 2001  
[Abstract]
[DOI] [Full Text]

Bimodal activation of SMC ATPase by intra- and inter-molecular interactions
Hirano M,
Anderson DE,
Erickson HP,
Hirano T

Embo Journal
  20 (12): 3238-3250; Jun 2001  
[Abstract]
[DOI] [Full Text]

Chromosome condensation by a human condensin complex in Xenopus egg extracts
Kimura K,
Cuvier O,
Hirano T

Journal of Biological Chemistry
  276 (8): 5417-5420; Feb 2001  
[Abstract]
[DOI] [Full Text]

Intermolecular DNA interactions stimulated by the cohesin complex in vitro: Implications for sister chromatid cohesion
Losada A,
Hirano T

Current Biology
  11 (4): 268-272; Feb 2001  
[Abstract]
[Full Text]

Biophysical characterization of structure and elasticity of mitotic chromosomes
Poirier MG,
Nemani AK,
Gupta P,
Marko JF,
Hirano T

Molecular Biology of the Cell
  11 (0): 437A-438A; Dec 2000  


HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions
Neuwald AF,
Hirano T

Genome Research
  10 (10): 1445-1452; Oct 2000  
[Abstract]
[Full Text]

Dual roles of the 11S regulatory subcomplex in condensin functions
Kimura K,
Hirano T

Proceedings of the National Academy of Sciences of the United States of America
  97 (22): 11972-11977; Oct 2000  
[Abstract]
[Full Text]

Biology in pictures. New light on sticky sisters
Losada A,
Hirano T

Curr Biol
  10 (17): R615; Sep 7 2000  
[DOI] [Full Text]

Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes
Losada A,
Yokochi T,
Kobayashi R,
Hirano T

Journal of Cell Biology
  150 (3): 405-416; Aug 2000   PMCID: 2175199
[Abstract]
[DOI] [Full Text] [PDF]

Chromosome cohesion, condensation, and separation
Hirano T

Annual Review of Biochemistry
  69 (0): 115-144; 2000  
[Abstract]
[Full Text]

[Evolutionary insights into chromosome condensation]
Hirano T

Tanpakushitsu Kakusan Koso
  44 (12): 1698-702; Sep 1999  
[Full Text]

13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation
Kimura K,
Rybenkov VV,
Crisona NJ,
Hirano T,
Cozzarelli NR

Cell
  98 (2): 239-48; Jul 23 1999  
[Abstract]
[Full Text]

SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates?
Hirano T

Genes Dev
  13 (1): 11-9; Jan 1 1999  
[Full Text]

ATP-dependent aggregation of single-stranded DNA by a bacterial SMC homodimer
Hirano M,
Hirano T

Embo J
  17 (23): 7139-48; Dec 1 1998  
[Abstract]
[Full Text]

Phosphorylation and activation of 13S condensin by Cdc2 in vitro
Kimura K,
Hirano M,
Kobayashi R,
Hirano T

Science
  282 (5388): 487-90; Oct 16 1998  
[Abstract]
[Full Text]

Identification of Xenopus SMC protein complexes required for sister chromatid cohesion
Losada A,
Hirano M,
Hirano T

Genes Dev
  12 (13): 1986-97; Jul 1 1998  
[Abstract]
[Full Text]

SMC protein complexes and higher-order chromosome dynamics
Hirano T

Curr Opin Cell Biol
  10 (3): 317-22; Jun 1998  
[Abstract]
[Full Text]

ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation
Kimura K,
Hirano T

Cell
  90 (4): 625-34; Aug 22 1997  
[Abstract]
[Full Text]

Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein
Hirano T,
Kobayashi R,
Hirano M

Cell
  89 (4): 511-21; May 16 1997  
[Abstract]
[Full Text]


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