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35 Article(s) on File
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Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann C,
Zuber J,
McJunkin K,
Chang K,
Malone CD,
Dickins R,
Xu Q,
Hengartner M,
Elledge SJ,
Hannon GJ,
Lowe SW

Molecular Cell
  41 (6): 733-746; Mar 18 2011   Array
[Abstract]
[DOI]

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase
Sendoel A,
Kohler I,
Fellmann C,
Lowe SW,
Hengartner MO

Nature
  465 (7298): 577-U69; Jun 3 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Epigenetic Regulation of Histone H3 Serine 10 Phosphorylation Status by HCF-1 Proteins in C. elegans and Mammalian Cells
Lee S,
Horn V,
Julien E,
Liu Y,
Wysocka J,
Bowerman B,
Hengartner MO,
Herr W

PLoS ONE
  2 (11): e1213; Nov 28 2007   PMCID: PMC2082077
[Abstract]
[DOI] [Full Text] [PDF]

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans
Hoeppner DJ,
Spector MS,
Ratliff TM,
Kinchen JM,
Granat S,
Lin SC,
Bhusri SS,
Conradt B,
Herman MA,
Hengartner MO

Dev Biol
  274 (1): 125-38; Oct 1 2004  
[Abstract]
[DOI]

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis
Hofmann ER,
Milstein S,
Boulton SJ,
Ye MJ,
Hofmann JJ,
Stergiou L,
Gartner A,
Vidal M,
Hengartner MO

Current Biology
  12 (22): 1908-1918; Nov 2002  
[Full Text]

The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis
Harrington RJ,
Gutch MJ,
Hengartner MO,
Tonks NK,
Chisholm AD

Development
  129 (9): 2141-2153; May 2002  
[Full Text]

Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity
Degtyareva NP,
Greenwell P,
Hofmann ER,
Hengartner MO,
Zhang L,
Culotti JG,
Petes TD

Proceedings of the National Academy of Sciences of the United States of America
  99 (4): 2158-2163; Feb 2002  
[Full Text]

CED-12/ELMO, a novel member of the crkII/dock180/rac pathway, is required for phagocytosis and cell migration
Gumienny TL,
Brugnera E,
Tosello-Trampont AC,
Kinchen JM,
Haney LB,
Nishiwaki K,
Walk SF,
Nemergut ME,
Macara IG,
Francis R,
Schedl T,
Qin Y,
Van Aelst L,
Hengartner MO,
Ravichandran KS

Cell
  107 (1): 27-41; Oct 2001  
[Abstract]
[Full Text]

jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans
Villanueva A,
Lozano J,
Morales A,
Lin XH,
Deng XZ,
Hengartner MO,
Kolesnick RN

Embo Journal
  20 (18): 5114-5128; Sep 2001  
[Abstract]
[Full Text]

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans
Hoeppner DJ,
Hengartner MO,
Schnabel R

Nature
  412 (6843): 202-206; Jul 2001  
[Abstract]
[DOI] [Full Text]

How the worm removes corpses: the nematode C-elegans as a model system to study engulfment
Gumienny TL,
Hengartner MO

Cell Death and Differentiation
  8 (6): 564-568; Jun 2001  
[Abstract]
[DOI] [Full Text]

Apoptosis: Corralling the corpses
Hengartner MO

Cell
  104 (3): 325-328; Feb 2001  
[Full Text]

A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C-elegans
Chung SB,
Gumienny TL,
Hengartner MO,
Driscoll M

Nature Cell Biology
  2 (12): 931-937; Dec 2000  
[Abstract]
[Full Text]

The biochemistry of apoptosis
Hengartner MO

Nature
  407 (6805): 770-776; Oct 2000  
[Abstract]
[Full Text]

A conserved checkpoint pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans
Gartner A,
Milstein S,
Ahmed S,
Hodgkin J,
Hengartner MO

Molecular Cell
  5 (3): 435-443; Mar 2000  
[Abstract]
[Full Text]

Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells
Su HP,
Brugnera E,
Van Criekinge W,
Smits E,
Hengartner M,
Bogaert T,
Ravichandran KS

Journal of Biological Chemistry
  275 (13): 9542-9549; Mar 2000  
[Abstract]
[Full Text]

DNA-damage-induced checkpoint pathways in the nematode Caenorhabditis elegans
Hofmann ER,
Milstein S,
Hengartner MO

Cold Spring Harbor Symposia on Quantitative Biology
  65 (0): 467-473; 2000  
[Full Text]

Apoptotic cell death: from worms to wombats ... but what about the weeds?
Hengartner MO,
Bryant JA
In:
Symp Soc Exp Biol
(ed. ) Cambridge: The Company of Biolo; 2000. 52: 1-12  


Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6
Liu QA,
Hengartner MO

Curr Biol
  9 (22): 1347-50; Nov 18 1999  
[Abstract]
[Full Text]

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis
Fraser AG,
James C,
Evan GI,
Hengartner MO

Curr Biol
  9 (6): 292-301; Mar 25 1999  
[Abstract]
[Full Text]

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline
Gumienny TL,
Lambie E,
Hartwieg E,
Horvitz HR,
Hengartner MO

Development
  126 (5): 1011-22; Feb 1999  
[Abstract]
[Full Text]

Selected elements of herpes simplex virus accessory factor HCF are highly conserved in Caenorhabditis elegans
Liu Y,
Hengartner MO,
Herr W

Mol Cell Biol
  19 (1): 909-15; Jan 1999  
[Abstract]
[Full Text]

The molecular mechanism of programmed cell death in C. elegans
Liu QA,
Hengartner MO

Ann N Y Acad Sci
  887 (0): 92-104; 1999  
[Abstract]
[Full Text]

Programmed cell death in the nematode C. elegans
Hengartner MO

Recent Prog Horm Res
  54 (0): 213-22; discussion 2; 1999  
[Abstract]
[Full Text]

Apoptosis. Death by crowd control
Hengartner M

Science
  281 (5381): 1298-9; Aug 28 1998  
[Full Text]

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans
Liu QA,
Hengartner MO

Cell
  93 (6): 961-72; Jun 12 1998  
[Abstract]
[Full Text]

The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development
Gutch MJ,
Flint AJ,
Keller J,
Tonks NK,
Hengartner MO

Genes Dev
  12 (4): 571-85; Feb 15 1998  
[Abstract]
[Full Text]

Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans
Hengartner MO

Exp Gerontol
  32 (4): 363-74; Jul-Oct 1997  
[Abstract]
[Full Text]

Interaction between the C. elegans cell-death regulators CED-9 and CED-4
Spector MS,
Desnoyers S,
Hoeppner DJ,
Hengartner MO

Nature
  385 (6617): 653-6; Feb 13 1997  
[Abstract]
[Full Text]

Orderly dismantling of a cell
Spector MS,
Hengartner MO

Apoptosis
  2 (3): 343-6; 1997  
[Full Text]

Apoptosis and the shape of death
Hengartner MO

Dev Genet
  21 (4): 245-8; 1997  
[Full Text]

Genetics of apoptosis
Desnoyers S,
Hengartner MO

Adv Pharmacol
  41 (0): 35-56; 1997  
[Full Text]

Programmed cell death: from development to disease. Meeting report
Hoeppner DJ,
Hengartner MO,
Fisher DE

Biochim Biophys Acta
  1242 (3): 217-20; Mar 18 1996  
[Full Text]

Programmed cell death in invertebrates
Hengartner MO

Curr Opin Genet Dev
  6 (1): 34-8; Feb 1996  
[Abstract]
[Full Text]

Programmed cell death in Caenorhabditis elegans
Hengartner MO,
Horvitz HR

Curr Opin Genet Dev
  4 (4): 581-6; Aug 1994  
[Abstract]
[DOI] [Full Text]


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