Cold Spring Harbor Library  CSHL: Home
   Home       Services       Archives       About Us   
 
CSHL Publication List
CSHL Authors Publications
Go back to Search Mode

          
Sort by   in order
250 Article(s) on File
Page 1 of 1
A Computational Algorithm to Predict shRNA Potency
Knott SR,
Maceli AR,
Erard N,
Chang K,
Marran K,
Zhou X,
Gordon A,
El Demerdash O,
Wagenblast E,
Kim S,
Fellmann C,
Hannon GJ

Mol Cell
  (0): Nov 25 2014   Nlm
[Abstract]
[DOI] [Full Text]

microRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development
Deng L,
Shang L,
Bai S,
Chen J,
He X,
Trevino RM,
Chen S,
Li X,
Meng X,
Yu B,
Wang X,
Liu Y,
McDermott SP,
Ariazi AE,
Ginestier C,
Ibarra I,
Ke J,
Luther TK,
Clouthier SG,
Xu L,
Shan G,
Song E,
Yao H,
Hannon GJ,
Weiss SJ,
Wicha MS,
Liu S

Cancer Research
  74 (22): 6648-6660; Nov 15 2014   Nlm
[Abstract]
[DOI] [Full Text]

Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence
Yang M,
Haase AD,
Huang FK,
Coulis G,
Rivera KD,
Dickinson BC,
Chang CJ,
Pappin DJ,
Neubert TA,
Hannon GJ,
Boivin B,
Tonks NK

Molecular Cell
  55 (5): 782-790; Aug 27 2014   Nlm
[Abstract]
[DOI] [Full Text]

A Genome-Wide Survey of Sexually Dimorphic Expression of Drosophila miRNAs Identifies the Steroid Hormone-Induced miRNA let-7 as a Regulator of Sexual Identity
Fagegaltier D,
Konig A,
Gordon A,
Lai EC,
Gingeras TR,
Hannon GJ,
Shcherbata HR

Genetics
  198 (2): 647-668; Jul 31 2014   Nlm
[Abstract]
[DOI] [Full Text]

Two waves of de novo methylation during mouse germ cell development
Molaro A,
Falciatori I,
Hodges E,
Aravin AA,
Marran K,
Rafii S,
McCombie WR,
Smith AD,
Hannon GJ

Genes Dev
  28 (14): 1544-9; Jul 15 2014   Nlm
[Abstract]
[DOI] [Full Text]

A genome-wide RNAi screen identifies factors required for distinct stages of C-elegans piRNA biogenesis
Goh WS,
Seah JW,
Harrison EJ,
Chen C,
Hammell CM,
Hannon GJ

Genes Development
  28 (7): 797-807; Apr 2014  
[Abstract]
[DOI] [Full Text]

An atlas of chromatoid body components
Meikar O,
Vagin VV,
Chalmel F,
Sostar K,
Lardenois A,
Hammell M,
Jin Y,
Da Ros M,
Wasik KA,
Toppari J,
Hannon GJ,
Kotaja N

RNA
  20 (4): 483-95; Apr 2014   NLM
[Abstract]
[DOI] [Full Text]

Slicer and the Argonautes
Faehnle CR,
Elkayam E,
Haase AD,
Hannon GJ,
Joshua-Tor L

Biophysical Journal
  106 (2): 455A-455A; Jan 28 2014   Thomson-Reuters
[Abstract]
[DOI] [Full Text]

Patient-derived tumor xenografts: Transforming clinical samples into mouse models
Siolas D,
Hannon GJ

Cancer Research
  73 (17): 5315-5319; Sep 2013   NLM
[Abstract]
[DOI] [Full Text]

Minotaur is critical for primary piRNA biogenesis
Vagin VV,
Yu Y,
Jankowska A,
Luo Y,
Wasik KA,
Malone CD,
Harrison E,
Rosebrock A,
Wakimoto BT,
Fagegaltier D,
Muerdter F,
Hannon GJ

RNA
  19 (8): 1064-1077; Aug 20 2013   NLM
[Abstract]
[DOI] [Full Text]

A Genomic-Scale Artificial MicroRNA Library as a Tool to Investigate the Functionally Redundant Gene Space in Arabidopsis
Hauser F,
Chen WX,
Deinlein U,
Chang K,
Ossowski S,
Fitz J,
Hannon GJ,
Schroeder JI

Plant Cell
  25 (8): 2848-2863; Aug 1 2013   NLM
[Abstract]
[DOI] [Full Text]

Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma
Wiggs JL,
Howell GR,
Linkroum K,
Abdrabou W,
Hodges E,
Braine CE,
Pasquale LR,
Hannon GJ,
Haines JL,
John SW

Clinical Genetics
  84 (2): 167; Aug 2013   NLM
[DOI] [Full Text]

Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates
Karginov FV,
Hannon GJ

Genes Dev
  27 (14): 1624-1632; Jul 15 2013   NLM
[Abstract]
[DOI] [Full Text]

De novo DNA demethylation and non-coding transcription define active intergenic regulatory elements
Schlesinger F,
Smith AD,
Gingeras TR,
Hannon GJ,
Hodges E

Genome Res
  23 (10): 1601-1614; Jun 28 2013   NLM
[Abstract]
[DOI] [Full Text]

Dnmt2-dependent methylomes lack defined DNA methylation patterns
Raddatz G,
Guzzardo PM,
Olova N,
Fantappié MR,
Rampp M,
Schaefer M,
Reik W,
Hannon GJ,
Lyko F

Proceedings of the National Academy of Sciences of the United States of America
  110 (21): 8627-8631; May 21 2013  
[DOI] [Full Text]

Molecular hierarchy of mammary differentiation yields refined markers of mammary stem cells
Dos Santos CO,
Rebbeck C,
Rozhkova E,
Valentine A,
Samuels A,
Kadiri LR,
Osten P,
Harris EY,
Uren PJ,
Smith AD,
Hannon GJ

Proc Natl Acad Sci U S A
  110 (18): 7123-7130; Apr 20 2013   NLM
[Abstract]
[DOI] [Full Text]

Drosophila H1 Regulates the Genetic Activity of Heterochromatin by Recruitment of Su(var)3-9
Lu XW,
Wontakal SN,
Kavi H,
Kim BJ,
Guzzardo PM,
Emelyanov AV,
Xu N,
Hannon GJ,
Zavadil J,
Fyodorov DV,
Skoultchi AI

Science
  340 (6128): 78-81; Apr 2013   TR
[Abstract]
[DOI] [Full Text]

Dogma derailed: the many influences of RNA on the genome
Sabin LR,
Delas MJ,
Hannon GJ

Mol Cell
  49 (5): 783-94; Mar 7 2013   Nlm
[Abstract]
[DOI] [Full Text]

Multiple roles for Piwi in silencing Drosophila transposons
Rozhkov NV,
Hammell M,
Hannon GJ

Genes and Development
  27 (4): 400-412; Feb 15 2013  
[Abstract]
[DOI] [Full Text]

Dicer-2 Processes Diverse Viral RNA Species
Sabin LR,
Zheng Q,
Thekkat P,
Yang J,
Hannon GJ,
Gregory BD,
Tudor M,
Cherry S

PLoS ONE
  8 (2): art. no e55458; Feb 12 2013  
[Abstract]
[DOI] [Full Text]

The piRNA pathway in flies: highlights and future directions
Guzzardo PM,
Muerdter F,
Hannon GJ

Curr Opin Genet Dev
  23 (1): 44-52; Jan 11 2013   NLM
[Abstract]
[DOI] [Full Text]

DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus
Kaaij LT,
van de Wetering M,
Fang F,
Decato B,
Molaro A,
van de Werken HJ,
van Es JH,
Schuijers J,
de Wit E,
de Laat W,
Hannon GJ,
Clevers HC,
Smith AD,
Ketting RF

Genome Biology
  14 (5): 2013   NLM
[Abstract]
[DOI] [Full Text]

Site identification in high-throughput RNA-protein interaction data
Uren PJ,
Bahrami-Samani E,
Burns SC,
Qiao M,
Karginov FV,
Hodges E,
Hannon GJ,
Sanford JR,
Penalva LO,
Smith AD

Bioinformatics
  28 (23): 3013-3120; Dec 1 2012   NLM
[Abstract]
[DOI] [Full Text]

Inducing RNAi in C. elegans by Feeding with dsRNA-expressing E. coli
Hammell CM,
Hannon GJ

Cold Spring Harb Protoc
  2012 (12): Dec 1 2012   NLM
[Abstract]
[DOI] [Full Text]

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis
Ipsaro JJ,
Haase AD,
Knott SR,
Joshua-Tor L,
Hannon GJ

Nature
  491 (7423): 279-83; Nov 8 2012   NLM
[Abstract]
[DOI] [Full Text]

Extreme Telomere Length Dimorphism in the Tasmanian Devil and Related Marsupials Suggests Parental Control of Telomere Length
Bender HS,
Murchison EP,
Pickett HA,
Deakin JE,
Strong MA,
Conlan C,
McMillan DA,
Neumann AA,
Greider CW,
Hannon GJ,
Reddel RR,
Graves JA

PLoS ONE
  7 (9): e46195; Sep 25 2012  
[Abstract]
[DOI] [Full Text]

An integrated encyclopedia of DNA elements in the human genome
Dunham I,
Kundaje A,
Aldred SF,
Collins PJ,
Davis C,
Doyle F,
Epstein CB,
Frietze S,
Harrow J,
Kaul R,
Khatun J,
Lajoie BR,
Landt SG,
Lee BK,
Pauli F,
Rosenbloom KR,
Sabo P,
Safi A,
Sanyal A,
Shoresh N,
Simon JM,
Song L,
Trinklein ND,
Altshuler RC,
Birney E,
Brown JB,
Cheng C,
Djebali S,
Dong XJ,
Ernst J,
Furey TS,
Gerstein M,
Giardine B,
Greven M,
Hardison RC,
Harris RS,
Herrero J,
Hoffman MM,
Iyer S,
Kellis M,
Kheradpour P,
Lassmann T,
Li QH,
Lin X,
Marinov GK,
Merkel A,
Mortazavi A,
Parker SC,
Reddy TE,
Rozowsky J,
Schlesinger F,
Thurman RE,
Wang J,
Ward LD,
Whitfield TW,
Wilder SP,
Wu W,
Xi HL,
Yip KY,
Zhuang JL,
Bernstein BE,
Green ED,
Gunter C,
Snyder M,
Pazin MJ,
Lowdon RF,
Dillon LA,
Adams LB,
Kelly CJ,
Zhang J,
Wexler JR,
Good PJ,
Feingold EA,
Crawford GE,
Dekker J,
Elnitski L,
Farnham PJ,
Giddings MC,
Gingeras TR,
Guigo R,
Hubbard TJ,
Kent WJ,
Lieb JD,
Margulies EH,
Myers RM,
Stamatoyannopoulos JA,
Tenenbaum SA,
Weng ZP,
White KP,
Wold B,
Yu Y,
Wrobel J,
Risk BA,
Gunawardena HP,
Kuiper HC,
Maier CW,
Xie L,
Chen X,
Mikkelsen TS,
Gillespie S,
Goren A,
Ram O,
Zhang XL,
Wang L,
Issner R,
Coyne MJ,
Durham T,
Ku M,
Truong T,
Eaton ML,
Davis CA,
Dobin A,
Tanzer A,
Lagarde J,
Lin W,
Xue CH,
Williams BA,
Zaleski C,
Roeder M,
Kokocinski F,
Abdelhamid RF,
Alioto T,
Antoshechkin I,
Baer MT,
Batut P,
Bell I,
Bell K,
Chakrabortty S,
Chrast J,
Curado J,
Derrien T,
Drenkow J,
Dumais E,
Dumais J,
Duttagupta R,
Fastuca M,
Fejes-Toth K,
Ferreira P,
Foissac S,
Fullwood MJ,
Gao H,
Gonzalez D,
Gordon A,
Howald C,
Jha S,
Johnson R,
Kapranov P,
King B,
Kingswood C,
Li GL,
Luo OJ,
Park E,
Preall JB,
Presaud K,
Ribeca P,
Robyr D,
Ruan XA,
Sammeth M,
Sandhu KS,
Schaeffer L,
See LH,
Shahab A,
Skancke J,
Suzuki AM,
Takahashi H,
Tilgner H,
Trout D,
Walters N,
Wang HE,
Yu YB,
Hayashizaki Y,
Reymond A,
Antonarakis SE,
Hannon GJ,
Ruan YJ,
Carninci P,
Sloan CA,
Learned K,
Malladi VS,
Wong MC,
Barber G,
Cline MS,
Dreszer TR,
Heitner SG,
Karolchik D,
Kirkup VM,
Meyer LR,
Long JC,
Maddren M,
Raney BJ,
Song LY,
Grasfeder LL,
Giresi PG,
Battenhouse A,
Sheffield NC,
Showers KA,
London D,
Bhinge AA,
Shestak C,
Schaner MR,
Kim SK,
Zhang ZZ,
Mieczkowski PA,
Mieczkowska JO,
Liu Z,
McDaniell RM,
Ni YY,
Rashid NU,
Kim MJ,
Adar S,
Zhang ZC,
Wang TY,
Winter D,
Keefe D,
Iyer VR,
Zheng MZ,
Wang P,
Gertz J,
Vielmetter J,
Partridge EC,
Varley KE,
Gasper C,
Bansal A,
Pepke S,
Jain P,
Amrhein H,
Bowling KM,
Anaya M,
Cross MK,
Muratet MA,
Newberry KM,
McCue K,
Nesmith AS,
Fisher-Aylor KI,
Pusey B,
DeSalvo G,
Parker SL,
Balasubramanian S,
Davis NS,
Meadows SK,
Eggleston T,
Newberry JS,
Levy SE,
Absher DM,
Wong WH,
Blow MJ,
Visel A,
Pennachio LA,
Petrykowska HM,
Abyzov A,
Aken B,
Barrell D,
Barson G,
Berry A,
Bignell A,
Boychenko V,
Bussotti G,
Davidson C,
Despacio-Reyes G,
Diekhans M,
Ezkurdia I,
Frankish A,
Gilbert J,
Gonzalez JM,
Griffiths E,
Harte R,
Hendrix DA,
Hunt T,
Jungreis I,
Kay M,
Khurana E,
Leng J,
Lin MF,
Loveland J,
Lu Z,
Manthravadi D,
Mariotti M,
Mudge J,
Mukherjee G,
Notredame C,
Pei BK,
Rodriguez JM,
Saunders G,
Sboner A,
Searle S,
Sisu C,
Snow C,
Steward C,
Tapanari E,
Tress ML,
van Baren MJ,
Washietl S,
Wilming L,
Zadissa A,
Zhang ZD,
Brent M,
Haussler D,
Valencia A,
Addleman N,
Alexander RP,
Auerbach RK,
Bettinger K,
Bhardwaj N,
Boyle AP,
Cao AR,
Cayting P,
Charos A,
Cheng Y,
Eastman C,
Euskirchen G,
Fleming JD,
Grubert F,
Habegger L,
Hariharan M,
Harmanci A,
Iyengar S,
Jin VX,
Karczewski KJ,
Kasowski M,
Lacroute P,
Lam H,
Lamarre-Vincent N,
Lian J,
Lindahl-Allen M,
Min RQ,
Miotto B,
Monahan H,
Moqtaderi Z,
Mu XM,
OGeen H,
Ouyang ZQ,
Patacsil D,
Raha D,
Ramirez L,
Reed B,
Shi MY,
Slifer T,
Witt H,
Wu LF,
Xu XQ,
Yan KK,
Yang XQ,
Struhl K,
Weissman SM,
Penalva LO,
Karmakar S,
Bhanvadia RR,
Choudhury A,
Domanus M,
Ma LJ,
Moran J,
Victorsen A,
Auer T,
Centanin L,
Eichenlaub M,
Gruhl F,
Heermann S,
Hoeckendorf B,
Inoue D,
Kellner T,
Kirchmaier S,
Mueller C,
Reinhardt R,
Schertel L,
Schneider S,
Sinn R,
Wittbrodt B,
Wittbrodt J,
Jain G,
Balasundaram G,
Bates DL,
Byron R,
Canfield TK,
Diegel MJ,
Dunn D,
Ebersol AK,
Frum T,
Garg K,
Gist E,
Hansen RS,
Boatman L,
Haugen E,
Humbert R,
Johnson AK,
Johnson EM,
Kutyavin TV,
Lee K,
Lotakis D,
Maurano MT,
Neph SJ,
Neri FV,
Nguyen ED,
Qu HZ,
Reynolds AP,
Roach V,
Rynes E,
Sanchez ME,
Sandstrom RS,
Shafer AO,
Stergachis AB,
Thomas S,
Vernot B,
Vierstra J,
Vong S,
Wang H,
Weaver MA,
Yan YQ,
Zhang MH,
Akey JM,
Bender M,
Dorschner MO,
Groudine M,
MacCoss MJ,
Navas P,
Stamatoyannopoulos G,
Beal K,
Brazma A,
Flicek P,
Johnson N,
Lukk M,
Luscombe NM,
Sobral D,
Vaquerizas JM,
Batzoglou S,
Sidow A,
Hussami N,
Kyriazopoulou-Panagi S,
Libbrecht MW,
Schaub MA,
Miller W,
Bickel PJ,
Banfai B,
Boley NP,
Huang HY,
Li JJ,
Noble WS,
Bilmes JA,
Buske OJ,
Sahu AD,
Kharchenko PV,
Park PJ,
Baker D,
Taylor J,
Lin XY,
Lochovsky L,
Min R,
Encode Project Conso

Nature
  489 (7414): 57-74; Sep 6 2012  
[Abstract]
[DOI] [Full Text]

Shutdown is a component of the Drosophila piRNA biogenesis machinery
Preall JB,
Czech B,
Guzzardo PM,
Muerdter F,
Hannon GJ

RNA
  18 (8): 1446-57; Aug 2012   Nlm
[Abstract]
[DOI] [Full Text]

The structure of human argonaute-2 in complex with miR-20a
Elkayam E,
Kuhn CD,
Tocilj A,
Haase AD,
Greene EM,
Hannon GJ,
Joshua-Tor L

Cell
  150 (1): 100-10; Jul 6 2012   NLM
[Abstract]
[DOI] [Full Text]

Proffered Paper: Next Generation RNAi Mouse Models for Drug Discovery and Toxicology Assessment
Premsrirut P,
Fellmann C,
Hannon GJ,
Lowe SW,
Zuber J,
Elledge S

European Journal of Cancer
  48 (0): S14-S14; Jul 2012  
[Full Text]

MicroRNA93 Regulates Proliferation and Differentiation of Normal and Malignant Breast Stem Cells
Liu S,
Patel SH,
Ginestier C,
Ibarra I,
Martin-Trevino R,
Bai S,
McDermott SP,
Shang L,
Ke J,
Ou SJ,
Heath A,
Zhang KJ,
Korkaya H,
Clouthier SG,
Charafe-Jauffret E,
Birnbaum D,
Hannon GJ,
Wicha MS

PLoS Genetics
  8 (6): e1002751; Jun 2012   Nlm
[Abstract]
[DOI] [Full Text]

Genomic landscape of human allele-specific DNA methylation
Fang F,
Hodges E,
Molaro A,
Dean M,
Hannon GJ,
Smith AD

Proceedings of the National Academy of Sciences of the United States of America
  109 (19): 7332-7337; May 2012  
[Abstract]
[DOI] [Full Text]

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection
Van Stry M,
Oguin TH,
Cheloufi S,
Vogel P,
Watanabe M,
Pillai MR,
Dash P,
Thomas PG,
Hannon GJ,
Bix M

Journal of Virology
  86 (15): 8344-8345; Apr 2012  
[DOI] [Full Text]

Modulators of Prostate Cancer Cell Proliferation and Viability Identified by Short-Hairpin RNA Library Screening
Dahlman KB,
Parker JS,
Shamu T,
Hieronymus H,
Chapinski C,
Carver B,
Chang K,
Hannon GJ,
Sawyers CL

PLoS ONE
  7 (4): Apr 11 2012  
[Abstract]
[DOI] [Full Text]

An alternative mode of microRNA target recognition
Chi SW,
Hannon GJ,
Darnell RB

Nat Struct Mol Biol
  19 (3): 321-327; Mar 2012   NLM
[Abstract]
[DOI] [Full Text]

A pipeline for the generation of shRNA transgenic mice
Dow LE,
Premsrirut PK,
Zuber J,
Fellmann C,
McJunkin K,
Miething C,
Park Y,
Dickins RA,
Hannon GJ,
Lowe SW

Nat Protoc
  7 (2): 374-93; Feb 2 2012   NLM
[Abstract]
[DOI] [Full Text]

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain
He M,
Liu Y,
Wang X,
Zhang MQ,
Hannon GJ,
Huang ZJ

Neuron
  73 (1): 35-48; Jan 12 2012   NLM
[Abstract]
[DOI] [Full Text]

Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy
Tan X,
Lu ZJ,
Gao G,
Xu QK,
Hu L,
Fellmann C,
Li MZ,
Qu HJ,
Lowe SW,
Hannon GJ,
Elledge SJ

Proceedings of the National Academy of Sciences of the United States of America
  109 (3): 869-874; Jan 2012  
[Abstract]
[DOI] [Full Text]

Production of artificial piRNAs in flies and mice
Muerdter F,
Olovnikov I,
Molaro A,
Rozhkov NV,
Czech B,
Gordon A,
Hannon GJ,
Aravin AA

RNA
  18 (1): 42-52; Jan 2012  
[Abstract]
[DOI] [Full Text]

Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1)
Liu-Sullivan N,
Zhang J,
Bakleh A,
Marchica J,
Li J,
Siolas D,
Laquerre S,
Degenhardt YY,
Wooster R,
Chang K,
Hannon GJ,
Powers S

Oncotarget
  2 (12): 1254-64; Dec 2011   Nlm
[Abstract]
[DOI] [Full Text]

Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas
Lee S,
Paulson KG,
Murchison EP,
Afanasiev OK,
Alkan C,
Leonard JH,
Byrd DR,
Hannon GJ,
Nghiem P

Journal of Clinical Virology
  52 (3): 272-275; Nov 2011   PMC3196837
[Abstract]
[DOI] [Full Text]

miR-34 miRNAs provide a barrier for somatic cell reprogramming
Choi YJ,
Lin CP,
Ho JJ,
He X,
Okada N,
Bu P,
Zhong Y,
Kim SY,
Bennett MJ,
Chen C,
Ozturk A,
Hicks GG,
Hannon GJ,
He L

Nature Cell Biology
  13 (11): 1353-1360 ; Nov 2011  
[Abstract]
[DOI] [Full Text]

Ancestral roles of small RNAs: an Ago-centric perspective
Joshua-Tor L,
Hannon GJ

Cold Spring Harb Perspect Biol
  3 (10): a003772; Oct 2011   NLM
[Abstract]
[DOI] [Full Text]

Sperm Methylation Profiles Reveal Features of Epigenetic Inheritance and Evolution in Primates
Molaro A,
Hodges E,
Fang F,
Song Q,
McCombie WR,
Hannon GJ,
Smith A

Cell
  146 (6): 1029-1041; Sep 16 2011   PMC3205962
[Abstract]
[DOI]

Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila
Zamparini AL,
Davis MY,
Malone CD,
Vieira E,
Zavadil J,
Sachidanandam R,
Hannon GJ,
Lehmann R

Development
  138 (18): 4039-4050; Sep 15 2011   PMC3160098
[Abstract]
[DOI]

Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles
Wang JB,
Czech B,
Crunk A,
Wallace A,
Mitreva M,
Hannon GJ,
Davis RE

Genome Research
  21 (9): 1462-1477; Sep 2011   PMC3166831
[Abstract]
[DOI]

Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection
Albert FW,
Hodges E,
Jensen JD,
Besnier F,
Xuan ZY,
Rooks M,
Bhattacharjee A,
Brizuela L,
Good JM,
Green RE,
Burbano HA,
Plyusnina IZ,
Trut L,
Andersson L,
Schoneberg T,
Carlborg O,
Hannon GJ,
Paabo S

Heredity
  107 (3): 205-214; Sep 2011  
[Abstract]
[DOI] [Full Text]

piRNA Production Requires Heterochromatin Formation in Drosophila
Rangan P,
Malone CD,
Navarro C,
Newbold SP,
Hayes PS,
Sachidanandam R,
Hannon GJ,
Lehmann R

Current Biology
  21 (16): 1373-1379; Aug 23 2011   PMC3205116
[Abstract]
[DOI] [Full Text]

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis
Tanaka T,
Hosokawa M,
Vagin VV,
Reuter M,
Hayashi E,
Mochizuki AL,
Kitamura K,
Yamanaka H,
Kondoh G,
Okawa K,
Kuramochi-Miyagawa S,
Nakano T,
Sachidanandam R,
Hannon GJ,
Pillai RS,
Nakatsuji N,
Chuma S

Proceedings of the National Academy of Sciences of the United States of America
  108 (26): 10579-10584; Jun 2011   PMC3127926
[Abstract]
[DOI]

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage
Spierings DC,
McGoldrick D,
Hamilton-Easton AM,
Neale G,
Murchison EP,
Hannon GJ,
Green DR,
Withoff S

Blood
  117 (20): 5340-5349; May 2011   PMC3109709
[Abstract]
[DOI]

A genome-scale shRNA resource for transgenic RNAi in Drosophila
Ni JQ,
Zhou R,
Czech B,
Liu LP,
Holderbaum L,
Yang-Zhou DH,
Shim HS,
Tao R,
Handler D,
Karpowicz P,
Binari R,
Booker M,
Brennecke J,
Perkins LA,
Hannon GJ,
Perrimon N

Nature Methods
  8 (5): 405-7; May 2011  
[Abstract]
[DOI]

Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis
Erlich Y,
Edvardson S,
Hodges E,
Zenvirt S,
Thekkat P,
Shaag A,
Dor T,
Hannon GJ,
Elpeleg O

Genome Research
  21 (5): 658-664; May 2011   PMCID: PMC3083082
[Abstract]
[DOI]

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Premsrirut PK,
Dow LE,
Kim SY,
Camiolo M,
Malone CD,
Miething C,
Scuoppo C,
Zuber J,
Dickins RA,
Kogan S,
Shroyer K,
Sordella R,
Hannon GJ,
Lowe SW

Cell
  145 (1): 145-158; Mar 31 2011   Elsevier
[Abstract]
[DOI]

Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma
Lachke SA,
Alkuraya FS,
Kneeland SC,
Ohn T,
Aboukhalil A,
Howell GR,
Saadi I,
Cavallesco R,
Yue YZ,
Tsai AC,
Nair KS,
Cosma MI,
Smith RS,
Hodges E,
AlFadhli SM,
Al-Hajeri A,
Shamseldin HE,
Behbehani A,
Hannon GJ,
Bulyk ML,
Drack AV,
Anderson PJ,
John SW,
Maas RL

Science
  331 (6024): 1571-1576; Mar 25 2011  
[Abstract]
[DOI]

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann C,
Zuber J,
McJunkin K,
Chang K,
Malone CD,
Dickins R,
Xu Q,
Hengartner M,
Elledge SJ,
Hannon GJ,
Lowe SW

Molecular Cell
  41 (6): 733-746; Mar 18 2011   Array
[Abstract]
[DOI]

FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR
Bivona TG,
Hieronymus H,
Parker J,
Chang K,
Taron M,
Rosell R,
Moonsamy P,
Dahlman K,
Miller VA,
Costa C,
Hannon GJ,
Sawyers CL

Nature
  471 (7339): 523-526; Mar 2011   ISI
[Abstract]
[DOI]

Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence
Berezikov E,
Robine N,
Samsonova A,
Westholm JO,
Naqvi A,
Hung JH,
Okamura K,
Dai Q,
Bortolamiol-Becet D,
Martin R,
Zhao YJ,
Zamore PD,
Hannon GJ,
Marra MA,
Weng ZP,
Perrimon N,
Lai EC

Genome Research
  21 (2): 203-215; Feb 2011   PMC3032924
[Abstract]
[DOI]

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
Zuber J,
McJunkin K,
Fellmann C,
Dow L,
Taylor MJ,
Hannon GJ,
Lowe SW

Nature Biotechnology
  29 (1): 79-85; Jan 2011  
[Abstract]
[DOI] [Full Text] [PDF]

Silencing of microRNA families by seed-targeting tiny LNAs
Obad S,
Dos Santos CO,
Petri A,
Heidenblad M,
Broom O,
Ruse I,
Fu C,
Lindow M,
Stenvang J,
Straarup EM,
Hansen HF,
Koch T,
Pappin J,
Hannon GJ,
Kauppinen S

Nature Genetics
  43 (4): 371-8; 2011   Elsevier
[Abstract]
[DOI] [Full Text]

Small RNA sorting: matchmaking for Argonautes
Czech B,
Hannon GJ

Nat Rev Genet
  12 (1): 19-31; Jan 2011  
[Abstract]
[DOI] [Full Text] [PDF]

Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila
Haase AD,
Fenoglio S,
Muerdter F,
Guzzardo PM,
Czech B,
Pappin DJ,
Chen C,
Gordon A,
Hannon GJ

Genes Dev
  24 (22): 2499-504; Oct 21 2010   PMCID: PMC2975926
[Abstract]
[DOI] [Full Text] [PDF]

Canonical and alternate functions of the microRNA biogenesis machinery
Chong MM,
Zhang GA,
Cheloufi S,
Neubert TA,
Hannon GJ,
Littman DR

Genes Development
  24 (17): 1951-1960; Sep 2010   PMC2932976
[Abstract]
[DOI] [Full Text] [PDF]

Small RNA-based silencing strategies for transposons in the process of invading Drosophila species
Rozhkov NV,
Aravin AA,
Zelentsova ES,
Schostak NG,
Sachidanandam R,
McCombie WR,
Hannon GJ,
Evgenev MB

RNA
  16 (8): 1634-1645; Aug 2010   PMCID: PMC2905761
[Abstract]
[DOI] [Full Text] [PDF]

Targeted enrichment of specific regions in the human genome by array hybridization
Igartua C,
Turner EH,
Ng SB,
Hodges E,
Hannon GJ,
Bhattacharjee A,
Rieder MJ,
Nickerson DA,
Shendure J

Current Protocols in Human Genetics
  66 (0): 18.3.1-18.3.14; Jul 2010   PMCID: PMC2910258
[Abstract]
[DOI] [Full Text] [PDF]

Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases
Karginov FV,
Cheloufi S,
Chong MM,
Stark A,
Smith AD,
Hannon GJ

Molecular Cell
  38 (6): 781-788; Jun 25 2010   PMCID: PMC2914474
[Abstract]
[DOI] [Full Text] [PDF]

A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity
Cifuentes D,
Xue HL,
Taylor DW,
Patnode H,
Mishima Y,
Cheloufi S,
Ma EB,
Mane S,
Hannon GJ,
Lawson ND,
Wolfe SA,
Giraldez AJ

Science
  328 (5986): 1694-1698; Jun 25 2010   PMC3093307
[Abstract]
[DOI] [Full Text] [PDF]

A Dicer-independent miRNA biogenesis pathway that requires Ago catalysis
Cheloufi S,
Dos Santos CO,
Chong MM,
Hannon GJ

Nature
  465 (7298): 584-9; Jun 3 2010   PMCID: PMC2995450
[Abstract]
[DOI] [Full Text] [PDF]

Molecular Evolution of piRNA and Transposon Control Pathways in Drosophila
Malone CD,
Hannon GJ

Cold Spring Harb Symp Quant Biol
  74 (0): 225-234; May 7 2010   PMC3181074
[Abstract]
[DOI] [Full Text] [PDF]

Targeted investigation of the neandertal genome by array-based sequence capture
Burbano HA,
Hodges E,
Green RE,
Briggs AW,
Krause J,
Meyer M,
Good JM,
Maricic T,
Johnson PL,
Xuan Z,
Rooks M,
Bhattacharjee A,
Brizuela L,
Albert FW,
De La Rasilla M,
Fortea J,
Rosas A,
Lachmann M,
Hannon GJ,
Paabo S

Science
  328 (5979): 723-725; May 7 2010   PMC3140021
[Abstract]
[DOI] [Full Text] [PDF]

The RNA interference system differently responds to the same mobile element in distant Drosophila species
Rozhkov NV,
Aravin AA,
Sachidanandam R,
Hannon GJ,
Sokolova ON,
Zelentsova ES,
Shostak NG,
Evgenev MB

Doklady Biochemistry and Biophysics
  431 (1): 79-81; Apr 18 2010   PMCID: PMC2998894
[DOI] [Full Text] [PDF]

Deep sequencing of target linkage assay-identified regions in familial breast cancer: Methods, analysis pipeline and troubleshooting
Rosa-Rosa JM,
Gracia-Azn√°rez FJ,
Hodges E,
Pita G,
Rooks M,
Xuan Z,
Bhattacharjee A,
Brizuela L,
Silva JM,
Hannon GJ,
Benitez J

PLoS ONE
  5 (4): e9976, 1-10; April 2010  
[Abstract]
[DOI]

Dicer is required in adult skin for maintenance of rapidly proliferating hair follicle matrix cells, hair shaft formation, and catagen
Teta M,
Choi Y,
Andl T,
Murchison EP,
Nagy A,
Hannon GJ,
Millar SE

Journal of Investigative Dermatology
  130 (0): 636; Apr 2010  
[Full Text]

The miRNA-processing enzyme Drosha is required for hair follicle regression, hair shaft differentiation, long-term maintenance of hair follicle stem cells, and epidermal homeostasis
Choi Y,
Nagy A,
Tam OH,
Hannon GJ,
Millar SE

Journal of Investigative Dermatology
  130 (0): 645; Apr 2010  
[Full Text]

Ancient animal microRNAs and the evolution of tissue identity
Christodoulou F,
Raible F,
Tomer R,
Simakov O,
Trachana K,
Klaus S,
Snyman H,
Hannon GJ,
Bork P,
Arendt D

Nature
  463 (7284): 1084-8; Feb 25 2010   PMCID: PMC2981144
[Abstract]
[DOI] [Full Text] [PDF]

Compressed genotyping
Erlich Y,
Gordon A,
Brand M,
Hannon GJ,
Mitra PP

IEEE Transactions on Information Theory
  56 (2): 706-723; Feb 2010   PMCID: PMC3065185
[Abstract]
[DOI] [Full Text]

Joubert Syndrome 2 (JBTS2) in Ashkenazi Jews Is Associated with a TMEM216 Mutation
Edvardson S,
Shaag A,
Zenvirt S,
Erlich Y,
Hannon GJ,
Shanske AL,
Gomori JM,
Ekstein J,
Elpeleg O

American Journal of Human Genetics
  86 (1): 93-97; Jan 8 2010   PMCID: PMC2801745
[Abstract]
[DOI] [Full Text] [PDF]

The CRISPR System: Small RNA-Guided Defense in Bacteria and Archaea
Karginov FV,
Hannon GJ

Molecular Cell
  37 (1): 7-19; Jan 5 2010   PMCID: PMC2819186
[Abstract]
[DOI] [Full Text] [PDF]

Evolutionary flux of canonical microRNAs and mirtrons in Drosophila
Berezikov E,
Liu N,
Flynt AS,
Hodges E,
Rooks M,
Hannon GJ,
Lai EC

Nature Genetics
  42 (1): 6-9; Jan 2010  
[DOI] [Full Text] [PDF]

The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer
Murchison EP,
Tovar C,
Hsu A,
Bender HS,
Kheradpour P,
Rebbeck CA,
Obendorf D,
Conlan C,
Bahlo M,
Blizzard CA,
Pyecroft S,
Kreiss A,
Kellis M,
Stark A,
Harkins TT,
Marshall Graves JA,
Woods GM,
Hannon GJ,
Papenfuss AT

Science
  327 (5961): 84-7; Jan 1 2010   PMCID: PMC2982769
[Abstract]
[DOI] [Full Text] [PDF]

Arginine methylation as a molecular signature of the Piwi small RNA pathway
Vagin VV,
Hannon GJ,
Aravin AA

Cell Cycle
  8 (24): 4003-4; Dec 15 2009   PMCID: PMC2993161


Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs
Rechavi O,
Erlich Y,
Amram H,
Flomenblit L,
Karginov FV,
Goldstein I,
Hannon GJ,
Kloog Y

Genes Dev
  23 (16): 1971-9; Dec 15 2009   PMCID: PMC2704425
[Abstract]
[DOI] [Full Text] [PDF]

miR-19 is a key oncogenic component of mir-17-92
Olive V,
Bennett MJ,
Walker JC,
Ma C,
Jiang I,
Cordon-Cardo C,
Li QJ,
Lowe SW,
Hannon GJ,
He L

Genes Development
  23 (24): 2839-2849; Dec 15 2009   PMC2800084
[Abstract]
[DOI] [Full Text] [PDF]

Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice
Aravin AA,
van der Heijden GW,
Castañeda J,
Vagin VV,
Hannon GJ,
Bortvin A

PLoS Genet
  5 (12): e1000764; Dec 2009  
[Abstract]
[DOI] [Full Text] [PDF]

Hierarchical rules for Argonaute loading in Drosophila
Czech B,
Zhou R,
Erlich Y,
Brennecke J,
Binari R,
Villalta C,
Gordon A,
Perrimon N,
Hannon GJ

Mol Cell
  36 (3): 445-56; Nov 13 2009   PMC2795325
[Abstract]
[DOI] [Full Text] [PDF]

Updates to the RMAP short-read mapping software
Smith AD,
Chung WY,
Hodges E,
Kendall JT,
Hannon GJ,
Hicks JB,
Xuan Z,
Zhang MQ

Bioinformatics
  25 (21): 2841-2842; Nov 1 2009   PMCID: PMC2895571
[Abstract]
[DOI] [Full Text] [PDF]

Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model
Bric A,
Miething C,
Bialucha CU,
Scuoppo C,
Zender L,
Krasnitz A,
Xuan Z,
Zuber J,
Wigler MH,
Hicks JB,
McCombie RW,
Hemann MT,
Hannon GJ,
Powers S,
Lowe SW

Cancer Cell
  16 (4): 324-35; Oct 6 2009   PMC2829755
[Abstract]
[DOI] [Full Text] [PDF]

Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
Zhou R,
Czech B,
Brennecke J,
Sachidanandam R,
Wohlschlegel JA,
Perrimon N,
Hannon GJ

RNA
  15 (10): 1886-1895; Oct 2009   PMCID: PMC2743050
[Abstract]
[DOI] [Full Text] [PDF]

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation
Fabian MR,
Mathonnet G,
Sundermeier T,
Mathys H,
Zipprich JT,
Svitkin YV,
Rivas F,
Jinek M,
Wohlschlegel J,
Doudna JA,
Chen CA,
Shyu A,
Yates Iii JR,
Hannon GJ,
Filipowicz W,
Duchaine TF,
Sonenberg N

Molecular Cell
  35 (6): 868-880 ; Sep 24 2009   PMCID: PMC2803087
[Abstract]
[DOI] [Full Text] [PDF]

The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response
Castellano L,
Giamas G,
Jacob J,
Coombes RC,
Lucchesi W,
Thiruchelvam P,
Barton G,
Jiao LR,
Wait R,
Waxman J,
Hannon GJ,
Stebbing J

Proc Natl Acad Sci U S A
  106 (37): 15732-15737; Sep 15 2009   PMCID: PMC2747188
[Abstract]
[DOI] [Full Text] [PDF]

High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing Dup removed 04/2012
Hodges E,
Smith AD,
Kendall JT,
Xuan Z,
Ravi K,
Rooks M,
Zhang MQ,
Ye K,
Bhattacharjee A,
Brizuela L,
McCombie WR,
Wigler MH,
Hannon GJ,
Hicks JB

Genome Res
  19 (9): 1593-1605; Sep 2009   PMCID: PMC2752124
[Abstract]
[DOI] [Full Text] [PDF]

Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila
Couvillion MT,
Lee SR,
Hogstad B,
Malone CD,
Tonkin LA,
Sachidanandam R,
Hannon GJ,
Collins K

Genes Dev
  23 (17): 2016-32; Sep 1 2009   PMCID: PMC2751968
[Abstract]
[DOI] [Full Text] [PDF]

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
Vagin VV,
Wohlschlegel J,
Qu J,
Jonsson Z,
Huang X,
Chuma S,
Girard A,
Sachidanandam R,
Hannon GJ,
Aravin AA

Genes Dev
  23 (15): 1749-62; Aug 1 2009   PMCID: PMC2720255