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30 Article(s) on File
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RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis
Cho H,
Herzka T,
Zheng W,
Qi J,
Wilkinson JE,
Bradner JE,
Robinson BD,
Castillo-Martin M,
Cordon-Cardo C,
Trotman LC

Cancer Discovery
  4 (3): 318-33; Mar 2014   Nlm
[Abstract]
[DOI] [Full Text]

RapidCaP, a novel GEM model for analysis and therapy of metastatic prostate cancer reveals Myc as a driver of Pten-mutant metastasis
Cho H,
Herzka T,
Zheng W,
Qi J,
Wilkinson JE,
Bradner JE,
Robinson BD,
Castillo-Martin M,
Cordon-Cardo C,
Trotman LC

Cancer Discov
  (0): Jan 27 2014   Nlm
[Abstract]
[DOI] [Full Text]

PTEN levels are controlled by a nuclear transport receptor in lung cancer
Chen MH,
Herzka TM,
Zeeman ME,
Plafker KS,
Minderer M,
Castillo-Martin M,
Cordon-Cardo C,
Plafker SM,
Trotman LC

Cancer Research
  73 (8): 5258; Apr 2013  
[Abstract]
[DOI] [Full Text]

Rapid Cap: A new generation of mouse models for prostate cancer
Cho HJ,
Herzka T,
Zheng W,
Castillo-Martin M,
Cordon-Cardo C,
Trotman LC

Cancer Research
  73 (8): 4091; Apr 2013  
[Abstract]
[DOI] [Full Text]

Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression
Chen MH,
Pratt CP,
Zeeman ME,
Schultz N,
Taylor BS,
ONeill A,
Castillo-Martin M,
Nowak DG,
Naguib A,
Grace DM,
Murn J,
Navin N,
Atwal GS,
Sander C,
Gerald WL,
Cordon-Cardo C,
Newton AC,
Carver BS,
Trotman LC

Cancer Cell
  20 (2): 173-186; Aug 2011   PMC3176728
[Abstract]
[DOI] [Full Text]

Distinct Expression Profiles of p63 Variants during Urothelial Development and Bladder Cancer Progression
Karni-Schmidt O,
Castillo-Martin M,
HuaiShen T,
Gladoun N,
Domingo-Domenech J,
Sanchez-Carbayo M,
Li Y,
Lowe SW,
Prives C,
Cordon-Cardo C

The American Journal of Pathology
  178 (3): 1350-1360; 2011   Elsevier PMC3069841
[Abstract]
[DOI]

miR-19 is a key oncogenic component of mir-17-92
Olive V,
Bennett MJ,
Walker JC,
Ma C,
Jiang I,
Cordon-Cardo C,
Li QJ,
Lowe SW,
Hannon GJ,
He L

Genes Development
  23 (24): 2839-2849; Dec 15 2009   PMC2800084
[Abstract]
[DOI] [Full Text] [PDF]

Cyfip1 is a putative invasion suppressor in epithelial cancers
Silva JM,
Ezhkova E,
Silva J,
Heart S,
Castillo M,
Campos Y,
Castro V,
Bonilla F,
Cordon-Cardo C,
Muthuswamy SK,
Powers S,
Fuchs E,
Hannon GJ

Cell
  137 (6): 1047-61; Jun 12 2009   PMCID: PMC2754270
[Abstract]
[DOI] [Full Text] [PDF]

DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma
Xue W,
Krasnitz A,
Lucito R,
Sordella R,
Van Aelst L,
Cordon-Cardo C,
Singer S,
Kuehnel F,
Wigler MH,
Powers S,
Zender L,
Lowe SW

Genes Dev
  22 (11): 1439-44; Jun 1 2008   PMCID: PMC2418580
[Abstract]
[DOI] [Full Text] [PDF]

Tissue-specific and reversible RNA interference in transgenic mice
Dickins RA,
McJunkin K,
Hernando E,
Premsrirut PK,
Krizhanovsky V,
Burgess DJ,
Kim SY,
Cordon-Cardo C,
Zender L,
Hannon GJ,
Lowe SW

Nat Genet
  39 (7): 914 - 921; Jul 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Role of the chromobox protein CBX7 in lymphomagenesis
Scott CL,
Gil J,
Hernando E,
Teruya-Feldstein J,
Narita M,
Martinez D,
Visakorpi T,
Mu D,
Cordon-Cardo C,
Peters G,
Beach D,
Lowe SW

Proc Natl Acad Sci U S A
  104 (13): 5389-94; Mar 27 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Xue W,
Zender L,
Miething C,
Dickins RA,
Hernando E,
Krizhanovsky V,
Cordon-Cardo C,
Lowe SW

Nature
  445 (7128): 656-660; Feb 2007  
[Abstract]
[DOI] [Full Text] [PDF]

Ubiquitination regulates PTEN nuclear import and tumor suppression
Trotman LC,
Wang X,
Alimonti A,
Chen Z,
Teruya-Feldstein J,
Yang H,
Pavletich NP,
Carver BS,
Cordon-Cardo C,
Erdjument-Bromage H,
Tempst P,
Chi SG,
Kim HJ,
Misteli T,
Jiang X,
Pandolfi PP

Cell
  128 (1): 141-56; Jan 12 2007   PMCID: PMC1855245
[Abstract]
[DOI] [Full Text] [PDF]

NEDD4-1 Is a Proto-Oncogenic Ubiquitin Ligase for PTEN
Wang X,
Trotman LC,
Koppie T,
Alimonti A,
Chen Z,
Gao Z,
Wang J,
Erdjument-Bromage H,
Tempst P,
Cordon-Cardo C,
Pandolfi PP,
Jiang X

Cell
  128 (1): 129-139; Jan 2007  
[Abstract]
[DOI] [Full Text]

P53 restoration in liver carcinomas induces cellular senescence and tumor clearance through an innate immune response
Zender L,
Xue W,
Cordon-Cardo C,
Lowe SW

Hepatology
  44 (4): 694A-695A; Oct 2006  
[DOI] [Full Text]

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
Zender L,
Spector MS,
Xue W,
Flemming P,
Cordon-Cardo C,
Silke J,
Fan ST,
Luk JM,
Wigler MH,
Hannon GJ,
Mu D,
Lucito R,
Powers S,
Lowe SW

Cell
  125 (7): 1253-67; Jun 30 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Identification of a tumour suppressor network opposing nuclear Akt function
Trotman LC,
Alimonti A,
Scaglioni PP,
Koutcher JA,
Cordon-Cardo C,
Pandolfi PP

Nature
  441 (7092): 523-527; May 25 2006  
[Abstract]
[DOI] [Full Text]

Apaf-1 expression in malignant melanoma [3]
Soengas MS,
Gerald WL,
Cordon-Cardo C,
Lazebnik Y,
Lowe SW

Cell Death and Differentiation
  13 (2): 352-353; 2006  
[DOI] [Full Text]

RNA interference against cancer associated genes
Hernando E,
Matushansky I,
Maki RG,
Lowe SW,
Cordon-Cardo C

Annals of Oncology
  17 (0): 45-45; 2006  
[Full Text]

Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma
Zender L,
Spector MS,
Xue W,
Flemming P,
Mu D,
Cordon-Cardo C,
Powers S,
Hannon GJ,
Lucito R,
Lowe SW

Hepatology
  42 (4): 244A-244A; Oct 2005  
[Full Text]

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
Chen Z,
Trotman LC,
Shaffer D,
Lin HK,
Dotan ZA,
Niki M,
Koutcher JA,
Scher HI,
Ludwig T,
Gerald W,
Cordon-Cardo C,
Pandolfi PP

Nature
  436 (7051): 725-30; Aug 4 2005   NLM
[Abstract]
[DOI] [Full Text]

Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors
Zender L,
Xue W,
Cordon-Cardo C,
Hannon GJ,
Lucito R,
Powers S,
Flemming P,
Spector MS,
Lowe SW

Cold Spring Harbor Symposia on Quantitative Biology VXX: Molecular approaches to controlling cancer
  70 251-261; 2005  
[Abstract]
[DOI] [Full Text] [PDF]

Role of Dok-1 and Dok-2 in leukemia suppression
Niki M,
Di Cristofano A,
Zhao M,
Honda H,
Hirai H,
Van Aelst L,
Cordon-Cardo C,
Pandolfi PP

J Exp Med
  200 (12): 1689-95; Dec 20 2004   PMCID: PMC2211998
[Abstract]
[DOI] [Full Text] [PDF]

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
Hernando E,
Nahle Z,
Juan G,
Diaz-Rodriguez E,
Alaminos M,
Hemann M,
Michel L,
Mittal V,
Gerald W,
Benezra R,
Lowe SW,
Cordon-Cardo C

Nature
  430 (7001): 797-802; Aug 2004  
[Abstract]
[DOI] [Full Text]

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
Wendel HG,
De Stanchina E,
Fridman JS,
Malina A,
Ray S,
Kogan S,
Cordon-Cardo C,
Pelletier J,
Lowe SW

Nature
  428 (6980): 332-7; Mar 18 2004  
[Abstract]
[DOI] [Full Text]

Tumor promotion by Mdm2 splice variants unable to bind p53
Fridman JS,
Hernando E,
Hemann MT,
de Stanchina E,
Cordon-Cardo C,
Lowe SW

Cancer Research
  63 (18): 5703-5706; Sep 2003  
[Abstract]
[Full Text]

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
Hemann MT,
Fridman JS,
Zilfou JT,
Hernando E,
Paddison PJ,
Cordon-Cardo C,
Hannon GJ,
Lowe SW

Nature Genetics
  33 (3): 396-400; Mar 1 2003  
[Abstract]
[DOI] [Full Text]

Pten dose dictates cancer progression in the prostate
Trotman LC,
Niki M,
Dotan ZA,
Koutcher JA,
Di Cristofano A,
Xiao A,
Khoo AS,
Roy-Burman P,
Greenberg NM,
Van Dyke T,
Cordon-Cardo C,
Pandolfi PP

Plos Biology
  1 (3): 2003  
[Abstract]
[DOI] [Full Text]

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
Soengas MS,
Capodieci P,
Polsky D,
Mora J,
Esteller M,
Opitz-Araya X,
McCombie R,
Herman JG,
Gerald WL,
Lazebnik YA,
Cordon-Cardo C,
Lowe SW

Nature
  409 (6817): 207-211; 2001  
[Abstract]
[DOI] [Full Text]

Role of the INK4a locus in tumor suppression and cell mortality
Serrano M,
Lee H,
Chin L,
Cordon-Cardo C,
Beach D,
DePinho RA

Cell
  85 (1): 27-37; Apr 5 1996  
[Abstract]
[Full Text]


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