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8 Article(s) on File
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Neutralization of terminal differentiation in gliomagenesis
Hu J,
Ho AL,
Yuan L,
Hu B,
Hua S,
Hwang SS,
Zhang J,
Hu T,
Zheng H,
Gan B,
Wu G,
Wang YA,
Chin L,
DePinho RA

Proceedings of the National Academy of Sciences of the United States of America
  110 (36): 14520-14527; Aug 5 2013   NLM
[Abstract]
[DOI] [Full Text]

Recapitulating human cancer in a mouse
Chin L,
De Sauvage F,
Egeblad M,
Olive KP,
Tuveson D,
Weiss W

Nature Biotechnology
  31 (5): 392-395; May 2013  
[DOI] [Full Text]

microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma
Genovese G,
Ergun A,
Shukla SA,
Campos B,
Hanna J,
Ghosh P,
Quayle SN,
Rai K,
Colla S,
Ying H,
Wu CJ,
Sarkar S,
Xiao Y,
Zhang J,
Zhang H,
Kwong L,
Dunn K,
Wiedemeyer WR,
Brennan C,
Zheng H,
Rimm DL,
Collins JJ,
Chin L

Cancer Discovery
  2 (8): 736-749; Jun 2012  
[Abstract]
[Full Text]

Towards patient-based cancer therapeutics
Schreiber SL,
Shamji AF,
Clemons PA,
Hon C,
Koehler AN,
Munoz B,
Palmer M,
Stern AM,
Wagner BK,
Powers S,
Lowe SW,
Guo X,
Krasnitz A,
Sawey ET,
Sordella R,
Stein LD,
Trotman LC,
Califano A,
Dalla-Favera R,
Ferrando A,
Iavarone A,
Pasqualucci L,
Silva J,
Stockwell BR,
Hahn WC,
Chin L,
DePinho RA,
Boehm JS,
Gopal S,
Huang A,
Root DE,
Weir BA,
Gerhard DS,
Zenklusen JC,
Roth MG,
White MA,
Minna JD,
MacMillan JB,
Posner BA

Nature Biotechnology
  28 (9): 904-906; Sep 2010   PMCID: PMC2939009
[DOI] [Full Text] [PDF]

Non-germline genetically engineered mouse models for translational cancer research
Heyer J,
Kwong LN,
Lowe SW,
Chin L

Nature Reviews Cancer
  10 (7): 470-480; Jul 2010  
[Abstract]
[DOI] [Full Text] [PDF]

Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma
Stegh AH,
Kim H,
Bachoo RM,
Forloney KL,
Zhang J,
Schulze H,
Park K,
Hannon GJ,
Yuan JY,
Louis DN,
DePinho RA,
Chin L

Genes Dev
  21 (1): 98-111; Jan 2007   PMCID: PMC1759904
[DOI] [Full Text] [PDF]

A genetic screen for candidate tumor suppressors identifies REST
Westbrook TF,
Martin ES,
Schlabach MR,
Leng YM,
Liang AC,
Feng B,
Zhao JJ,
Roberts TM,
Mandel G,
Hannon GJ,
DePinho RA,
Chin L,
Elledge SJ

Cell
  121 (6): 837-848; Jun 2005  
[Abstract]
[DOI] [Full Text]

Role of the INK4a locus in tumor suppression and cell mortality
Serrano M,
Lee H,
Chin L,
Cordon-Cardo C,
Beach D,
DePinho RA

Cell
  85 (1): 27-37; Apr 5 1996  
[Abstract]
[Full Text]


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