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8 Article(s) on File
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Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation
Chandra T,
Kirschner K,
Thuret J,
Pope B,
Ryba T,
Newman S,
Ahmed K,
Samarajiwa S,
Salama R,
Carroll T,
Stark R,
Janky R,
Narita M,
Xue L,
Chicas A,
Nũnez S,
Janknecht R,
Hayashi-Takanaka Y,
Wilson M,
Marshall A,
Odom D,
Babu M,
Bazett-Jones D,
Tavaré S,
Edwards PW,
Lowe S,
Kimura H,
Gilbert D

Molecular Cell
  47 (2): 203-214; Jul 27 2012  
[Abstract]
[DOI] [Full Text]

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence
Aksoy O,
Chicas A,
Zeng T,
Zhao Z,
McCurrach M,
Wang X,
Lowe SW

Genes Dev
  26 (14): 1546-57; Jul 15 2012   Nlm
[Abstract]
[DOI] [Full Text]

H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
Chicas A,
Kapoor A,
Wang XW,
Aksoy O,
Evertts AG,
Zhang MQ,
Garcia BA,
Bernstein E,
Lowe SW

Proceedings of the National Academy of Sciences of the United States of America
  109 (23): 8971-8976; Jun 5 2012  
[Abstract]
[DOI] [Full Text]

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
Freed-Pastor WA,
Mizuno H,
Zhao X,
Langerød A,
Moon SH,
Rodriguez-Barrueco R,
Barsotti A,
Chicas A,
Li W,
Polotskaia A,
Bissell MJ,
Osborne TF,
Tian B,
Lowe SW,
Silva JM,
Børresen-Dale AL,
Levine AJ,
Bargonetti J,
Prives C

Cell
  148 (1): 244-258; Jan 2012  
[Abstract]
[DOI] [Full Text]

Control of the senescence-associated secretory phenotype by NF-{kappa}B promotes senescence and enhances chemosensitivity
Chien Y,
Scuoppo C,
Wang X,
Fang X,
Balgley B,
Bolden JE,
Premsrirut P,
Luo W,
Chicas A,
Lee CS,
Kogan SC,
Lowe SW

Genes Dev
  25 (20): 2125-2136; Oct 15 2011   NLM
[Abstract]
[DOI]

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Zuber J,
Shi J,
Wang E,
Rappaport AR,
Herrmann H,
Sison EA,
Magoon D,
Qi J,
Blatt K,
Wunderlich M,
Taylor MJ,
Johns C,
Chicas A,
Mulloy JC,
Kogan SC,
Brown P,
Valent P,
Bradner JE,
Lowe SW,
Vakoc CR

Nature
  478 (7370): 524-528; Aug 3 2011   NLM
[Abstract]
[DOI]

p16INK4a-mediated suppression of telomerase in normal and malignant human breast cells
Bazarov AV,
van Sluis M,
Hines WC,
Bassett E,
Beliveau A,
Campeau E,
Mukhopadhyay R,
Lee WJ,
Melodyev S,
Zaslavsky Y,
Lee L,
Rodier F,
Chicas A,
Lowe SW,
Benhattar J,
Ren B,
Campisi J,
Yaswen P

Aging Cell
  9 (5): 736-746; Oct 2010   PMC2941554
[Abstract]
[DOI] [Full Text]

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence
Chicas A,
Wang X,
Zhang C,
McCurrach ME,
Zhao Z,
Mert O,
Dickins RA,
Narita M,
Zhang MQ,
Lowe SW

Cancer Cell
  17 (4): 376-387; Apr 12 2010   PMCID: PMC2889489
[Abstract]
[DOI] [Full Text] [PDF]


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