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31 Article(s) on File
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Cell death machinery makes life more robust
Aguirre-Chen C,
Hammell CM

Elife
  3 (0): Dec 30 2014   Nlm
[Abstract]
[DOI] [Full Text]

LIN-42, the Caenorhabditis elegans PERIOD homolog, Negatively Regulates MicroRNA Transcription
Perales R,
King DM,
Aguirre-Chen C,
Hammell CM

PLoS Genet
  10 (7): e1004486; Jul 2014   Nlm
[Abstract]
[DOI] [Full Text]

Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel
Delaneau O,
Marchini J,
McVeanh GA,
Donnelly P,
Lunter G,
Marchini JL,
Myers S,
Gupta-Hinch A,
Iqbal Z,
Mathieson I,
Rimmer A,
Xifara DK,
Kerasidou A,
Churchhouse C,
Altshuler DM,
Gabriel SB,
Lander ES,
Gupta N,
Daly MJ,
DePristo MA,
Banks E,
Bhatia G,
Carneiro MO,
Del Angel G,
Genovese G,
Handsaker RE,
Hartl C,
McCarroll SA,
Nemesh JC,
Poplin RE,
Schaffner SF,
Shakir K,
Sabeti PC,
Grossman SR,
Tabrizi S,
Tariyal R,
Li H,
Reich D,
Durbin RM,
Hurles ME,
Balasubramaniam S,
Burton J,
Danecek P,
Keane TM,
Kolb-Kokocinski A,
McCarthy S,
Stalker J,
Quail M,
Ayub Q,
Chen Y,
Coffey AJ,
Colonna V,
Huang N,
Jostins L,
Scally A,
Walter K,
Xue Y,
Zhang Y,
Blackburne B,
Lindsay SJ,
Ning Z,
Frankish A,
Harrow J,
Chris TS,
Abecasis GR,
Kang HM,
Anderson P,
Blackwell T,
Busonero F,
Fuchsberger C,
Jun G,
Maschio A,
Porcu E,
Sidore C,
Tan A,
Trost MK,
Bentley DR,
Grocock R,
Humphray S,
James T,
Kingsbury Z,
Bauer M,
Cheetham RK,
Cox T,
Eberle M,
Murray L,
Shaw R,
Chakravarti A,
Clark AG,
Keinan A,
Rodriguez-Flores JL,
De LaVega FM,
Degenhardt J,
Eichler EE,
Flicek P,
Clarke L,
Leinonen R,
Smith RE,
Zheng-Bradley X,
Beal K,
Cunningham F,
Herrero J,
McLaren WM,
Ritchie GR,
Barker J,
Kelman G,
Kulesha E,
Radhakrishnan R,
Roa A,
Smirnov D,
Streeter I,
Toneva I,
Gibbs RA,
Dinh H,
Kovar C,
Lee S,
Lewis L,
Muzny D,
Reid J,
Wang M,
Yu F,
Bainbridge M,
Challis D,
Evani US,
Lu J,
Nagaswamy U,
Sabo A,
Wang Y,
Yu J,
Fowler G,
Hale W,
Kalra D,
Green ED,
Knoppers BM,
Korbel JO,
Rausch T,
Sttz AM,
Lee C,
Griffin L,
Hsieh CH,
Mills RE,
Von Grotthuss M,
Zhang C,
Shi X,
Lehrach H,
Sudbrak R,
Amstislavskiy VS,
Lienhard M,
Mertes F,
Sultan M,
Timmermann B,
Yaspo ML,
Herwig SR,
Mardis ER,
Wilson RK,
Fulton L,
Fulton R,
Weinstock GM,
Chinwalla A,
Ding L,
Dooling D,
Koboldt DC,
McLellan MD,
Wallis JW,
Wendl MC,
Zhang Q,
Marth GT,
Garrison EP,
Kural D,
Lee WP,
Leong WF,
Ward AN,
Wu J,
Zhang M,
Nickerson DA,
Alkan C,
Hormozdiari F,
Ko A,
Sudmant PH,
Schmidt JP,
Davies CJ,
Gollub J,
Webster T,
Wong B,
Zhan Y,
Sherry ST,
Xiao C,
Church D,
Ananiev V,
Belaia Z,
Beloslyudtsev D,
Bouk N,
Chen C,
Cohen R,
Cook C,
Garner J,
Hefferon T,
Kimelman M,
Liu C,
Lopez J,
Meric P,
Ostapchuk Y,
Phan L,
Ponomarov S,
Schneider V,
Shekhtman E,
Sirotkin K,
Slotta D,
Zhang H,
Wang J,
Fang X,
Guo X,
Jian M,
Jiang H,
Jin X,
Li G,
Li J,
Li Y,
Liu X,
Lu Y,
Ma X,
Tai S,
Tang M,
Wang B,
Wang G,
Wu H,
Wu R,
Yin Y,
Zhang W,
Zhao J,
Zhao M,
Zheng X,
Lachlan H,
Fang L,
Li Q,
Li Z,
Lin H,
Liu B,
Luo R,
Shao H,
Xie Y,
Ye C,
Yu C,
Zheng H,
Zhu H,
Cai H,
Cao H,
Su Y,
Tian Z,
Yang H,
Yang L,
Zhu J,
Cai Z,
Albrecht MW,
Borodina TA,
Auton A,
Yoon SC,
Lihm J,
Makarov V,
Jin H,
Kim W,
Kim KC,
Gottipati S,
Jones D,
Cooper DN,
Ball EV,
Stenson PD,
Barnes B,
Kahn S,
Ye K,
Batzer MA,
Konkel MK,
Walker JA,
MacArthur DG,
Lek M,
Shriver MD,
Bustamante CD,
Gravel S,
Kenny EE,
Kidd JM,
Lacroute P,
Maples BK,
Moreno-Estrada A,
Zakharia F,
Henn B,
Sandoval K,
Byrnes JK,
Halperin E,
Baran Y,
Craig DW,
Christoforides A,
Izatt T,
Kurdoglu AA,
Sinari SA,
Homer N,
Squire K,
Sebat J,
Bafna V,
Burchard EG,
Hernandez RD,
Gignoux CR,
Haussler D,
Katzman SJ,
Kent WJ,
Howie B,
Ruiz-Linares A,
Dermitzakis ET,
Lappalainen T,
Devine SE,
Maroo A,
Tallon LJ,
Rosenfeld JA,
Michelson LP,
Angius A,
Cucca F,
Sanna S,
Bigham A,
Jones C,
Reinier F,
Lyons R,
Schlessinger D,
Awadalla P,
Hodgkinson A,
Oleksyk TK,
Martinez-Cruzado JC,
Fu Y,
Xiong M,
Jorde L,
Witherspoon D,
Xing J,
Browning BL,
Hajirasouliha I,
Chen K,
Albers CA,
Gerstein MB,
Abyzov A,
Chen J,
Habegger L,
Harmanci AO,
Mu XJ,
Sisu C,
Balasubramanian S,
Jin M,
Khurana E,
Clarke D,
Michaelson JJ,
Osullivan C,
Barnes KC,
Gharani N,
Toji LH,
Gerry N,
Kaye JS,
Kent A,
Mathias R,
Ossorio PN,
Parker M,
Rotimi CN,
Royal CD,
Tishkoff S,
Via M,
Bodmer W,
Bedoya G,
Yang G,
You CJ,
Garcia-Montero A,
Orfao A,
Dutil J,
Brooks LD,
Felsenfeld AL

Nature Communications
  5 (0): Jun 13 2014   Elsevier
[Abstract]
[DOI] [Full Text]

MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia
Chen C,
Liu Y,
Rappaport AR,
Kitzing T,
Schultz N,
Zhao Z,
Shroff AS,
Dickins RA,
Vakoc CR,
Bradner JE,
Stock W,
LeBeau MM,
Shannon KM,
Kogan S,
Zuber J,
Lowe SW

Cancer Cell
  25 (5): 652-65; May 1 2014   Nlm
[Abstract]
[DOI] [Full Text]

MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
Chen C,
Liu Y,
Rappaport AR,
Kitzing T,
Schultz N,
Zhao Z,
Shroff AS,
Dickins RA,
Vakoc CR,
Bradner JE,
Stock W,
Lebeau MM,
Shannon KM,
Kogan S,
Zuber J,
Lowe SW

Cancer Cell
  25 (5): 652-665; Apr 30 2014   NLM
[Abstract]
[DOI] [Full Text]

A genome-wide RNAi screen identifies factors required for distinct stages of C-elegans piRNA biogenesis
Goh WS,
Seah JW,
Harrison EJ,
Chen C,
Hammell CM,
Hannon GJ

Genes Development
  28 (7): 797-807; Apr 2014  
[Abstract]
[DOI] [Full Text]

A Genome-wide RNAi Screen Draws a Genetic Framework for Transposon Control and Primary piRNA Biogenesis in Drosophila
Muerdter F,
Guzzardo PM,
Gillis J,
Luo Y,
Yu Y,
Chen C,
Fekete R,
Hannon G

Molecular Cell
  50 (5): 736-748; Jun 6 2013   Elsevier
[Abstract]
[DOI] [Full Text]

Evaluation of methods for modeling transcription factor sequence specificity
Weirauch MT,
Cote A,
Norel R,
Annala M,
Zhao Y,
Riley TR,
Saez-Rodriguez J,
Cokelaer T,
Vedenko A,
Talukder S,
Bussemaker HJ,
Quaid MD,
Bulyk ML,
Stolovitzky G,
Hughes TR,
Agius P,
Arvey A,
Bucher P,
Callan Jr CG,
Chang CW,
Chen CY,
Chen YS,
Chu YW,
Grau J,
Grosse I,
Jagannathan V,
Keilwagen J,
Kiebasa SM,
Kinney JB,
Klein H,
Kursa MB,
Lähdesmäki H,
Laurila K,
Lei C,
Leslie C,
Linhart C,
Murugan A,
Myšičková A,
Noble WS,
Nykter M,
Orenstein Y,
Posch S,
Ruan J,
Rudnicki WR,
Schmid CD,
Shamir R,
Sung WK,
Vingron M,
Zhang Z

Nature Biotechnology
  31 (2): 126-134; Feb 2013  
[Abstract]
[DOI] [Full Text]

An integrated map of genetic variation from 1,092 human genomes
Altshuler DM,
Durbin RM,
Abecasis GR,
Bentley DR,
Chakravarti A,
Clark AG,
Donnelly P,
Eichler EE,
Flicek P,
Gabriel SB,
Gibbs RA,
Green ED,
Hurles ME,
Knoppers BM,
Korbel JO,
Lander ES,
Lee C,
Lehrach H,
Mardis ER,
Marth GT,
McVean GA,
Nickerson DA,
Schmidt JP,
Sherry ST,
Wang J,
Wilson RK,
Dinh H,
Kovar C,
Lee S,
Lewis L,
Muzny D,
Reid J,
Wang M,
Fang XD,
Guo XS,
Jian M,
Jiang H,
Jin X,
Li GQ,
Li JX,
Li YR,
Li Z,
Liu X,
Lu Y,
Ma XD,
Su Z,
Tai SS,
Tang MF,
Wang B,
Wang GB,
Wu HL,
Wu RH,
Yin Y,
Zhang WW,
Zhao J,
Zhao MR,
Zheng XL,
Zhou Y,
Gupta N,
Clarke L,
Leinonen R,
Smith RE,
Zheng-Bradley X,
Grocock R,
Humphray S,
James T,
Kingsbury Z,
Sudbrak R,
Albrecht MW,
Amstislavskiy VS,
Borodina TA,
Lienhard M,
Mertes F,
Sultan M,
Timmermann B,
Yaspo ML,
Fulton L,
Fulton R,
Weinstock GM,
Balasubramaniam S,
Burton J,
Danecek P,
Keane TM,
Kolb-Kokocinski A,
McCarthy S,
Stalker J,
Quail M,
Davies CJ,
Gollub J,
Webster T,
Wong B,
Zhan YP,
Auton A,
Yu F,
Bainbridge M,
Challis D,
Evani US,
Lu J,
Nagaswamy U,
Sabo A,
Wang Y,
Yu J,
Coin LJ,
Fang L,
Li QB,
Li ZY,
Lin HX,
Liu BH,
Luo RB,
Qin N,
Shao HJ,
Wang BQ,
Xie YL,
Ye C,
Yu C,
Zhang F,
Zheng HC,
Zhu HM,
Garrison EP,
Kural D,
Lee WP,
Leong WF,
Ward AN,
Wu JT,
Zhang MY,
Griffin L,
Hsieh CH,
Mills RE,
Shi XH,
von Grotthuss M,
Zhang CS,
Daly MJ,
DePristo MA,
Banks E,
Bhatia G,
Carneiro MO,
del Angel G,
Genovese G,
Handsaker RE,
Hartl C,
McCarroll SA,
Nemesh JC,
Poplin RE,
Schaffner SF,
Shakir K,
Yoon SC,
Lihm J,
Makarov V,
Jin HJ,
Kim W,
Kim KC,
Rausch T,
Beal K,
Cunningham F,
Herrero J,
McLaren WM,
Ritchie GR,
Gottipati S,
Keinan A,
Rodriguez-Flores JL,
Sabeti PC,
Grossman SR,
Tabrizi S,
Tariyal R,
Cooper DN,
Ball EV,
Stenson PD,
Barnes B,
Bauer M,
Cheetham RK,
Cox T,
Eberle M,
Kahn S,
Murray L,
Peden J,
Shaw R,
Ye K,
Batzer MA,
Konkel MK,
Walker JA,
MacArthur DG,
Lek M,
Herwig R,
Shriver MD,
Bustamante CD,
Byrnes JK,
De la Vega FM,
Gravel S,
Kenny EE,
Kidd JM,
Lacroute P,
Maples BK,
Moreno-Estrada A,
Zakharia F,
Halperin E,
Baran Y,
Craig DW,
Christoforides A,
Homer N,
Izatt T,
Kurdoglu AA,
Sinari SA,
Squire K,
Xiao CL,
Sebat J,
Bafna V,
Burchard EG,
Hernandez RD,
Gignoux CR,
Haussler D,
Katzman SJ,
Kent WJ,
Howie B,
Ruiz-Linares A,
Dermitzakis ET,
Lappalainen T,
Devine SE,
Liu XY,
Maroo A,
Tallon LJ,
Rosenfeld JA,
Michelson LP,
Kang HM,
Anderson P,
Angius A,
Bigham A,
Blackwell T,
Busonero F,
Cucca F,
Fuchsberger C,
Jones C,
Jun G,
Li Y,
Lyons R,
Maschio A,
Porcu E,
Reinier F,
Sanna S,
Schlessinger D,
Sidore C,
Tan A,
Trost MK,
Awadalla P,
Hodgkinson A,
Lunter G,
Marchini JL,
Myers S,
Churchhouse C,
Delaneau O,
Gupta-Hinch A,
Iqbal Z,
Mathieson I,
Rimmer A,
Xifara DK,
Oleksyk TK,
Fu YX,
Liu XM,
Xiong MM,
Jorde L,
Witherspoon D,
Xing JC,
Browning BL,
Alkan C,
Hajirasouliha I,
Hormozdiari F,
Ko A,
Sudmant PH,
Chen K,
Chinwalla A,
Ding L,
Dooling D,
Koboldt DC,
McLellan MD,
Wallis JW,
Wendl MC,
Zhang QY,
Tyler-Smith C,
Albers CA,
Ayub Q,
Chen Y,
Coffey AJ,
Colonna V,
Huang N,
Jostins L,
Li H,
Scally A,
Walter K,
Xue YL,
Zhang YJ,
Gerstein MB,
Abyzov A,
Balasubramanian S,
Chen JM,
Clarke D,
Fu Y,
Habegger L,
Harmanci AO,
Jin MK,
Khurana E,
Mu XJ,
Sisu C,
Degenhardt J,
Stutz AM,
Church D,
Michaelson JJ,
Ben B,
Lindsay SJ,
Ning ZM,
Yu FL,
Frankish A,
Harrow J,
Fowler G,
Hale W,
Kalra D,
Guo X,
Li G,
Zheng X,
Barker J,
Kelman G,
Kulesha E,
Radhakrishnan R,
Roa A,
Smirnov D,
Streeter I,
Toneva I,
Vaughan B,
Ananiev V,
Belaia Z,
Beloslyudtsev D,
Bouk N,
Chen C,
Cohen R,
Cook C,
Garner J,
Hefferon T,
Kimelman M,
Liu C,
Lopez J,
Meric P,
OSullivan C,
Ostapchuk Y,
Phan L,
Ponomarov S,
Schneider V,
Shekhtman E,
Sirotkin K,
Slotta D,
Zhang H,
Barnes KC,
Beiswanger C,
Cai HY,
Cao HZ,
Gharani N,
Henn B,
Jones D,
Kaye JS,
Kent A,
Kerasidou A,
Mathias R,
Ossorio PN,
Parker M,
Reich D,
Rotimi CN,
Royal CD,
Sandoval K,
Su YY,
Tian ZM,
Tishkoff S,
Toji LH,
Via M,
Wang YH,
Yang HM,
Yang L,
Zhu JY,
Bodmer W,
Bedoya G,
Ming CZ,
Yang G,
You CJ,
Peltonen L,
Garcia-Montero A,
Orfao A,
Dutil J,
Martinez-Cruzado JC,
Brooks LD,
Felsenfeld AL,
McEwen JE,
Clemm NC,
Duncanson A,
Dunn M,
Guyer MS,
Peterson JL,
Genomes Project C

Nature
  491 (7422): 56-65; Nov 1 2012  
[Abstract]
[DOI] [Full Text]

ZmCCT and the genetic basis of day-length adaptation underlying the postdomestication spread of maize
Hung HY,
Shannon LM,
Tian F,
Bradbury PJ,
Chen C,
Flint-Garcia SA,
McMullen MD,
Ware D,
Buckler ES,
Doebley JF,
Holland JB

Proceedings of the National Academy of Sciences of the United States of America
  109 (28): E1913-E1921; Jul 10 2012  
[Abstract]
[DOI] [Full Text]

miR-34 miRNAs provide a barrier for somatic cell reprogramming
Choi YJ,
Lin CP,
Ho JJ,
He X,
Okada N,
Bu P,
Zhong Y,
Kim SY,
Bennett MJ,
Chen C,
Ozturk A,
Hicks GG,
Hannon GJ,
He L

Nature Cell Biology
  13 (11): 1353-1360 ; Nov 2011  
[Abstract]
[DOI] [Full Text]

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
Zuber J,
Rappaport AR,
Luo W,
Wang E,
Chen C,
Vaseva AV,
Shi J,
Weissmueller S,
Fellman C,
Taylor MJ,
Weissenboeck M,
Graeber TG,
Kogan SC,
Vakoc CR,
Lowe SW

Genes Dev
  25 (15): 1628-1640; Aug 1 2011  
[Abstract]
[DOI]

The Tuberous Sclerosis Complex-Mammalian Target of Rapamycin Pathway Maintains the Quiescence and Survival of Naive T Cells
Wu Q,
Liu Y,
Chen C,
Ikenoue T,
Qiao Y,
Li CS,
Li WQ,
Guan KL,
Zheng P

Journal of Immunology
  187 (3): 1106-1112; Aug 2011   PMC3151493
[Abstract]
[DOI]

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
Darnell JC,
Van Driesche SJ,
Zhang C,
Hung KY,
Mele A,
Fraser CE,
Stone EF,
Chen C,
Fak JJ,
Chi SW,
Licatalosi DD,
Richter JD,
Darnell RB

Cell
  146 (2): 247-261; Jul 2011  
[Abstract]
[DOI]

Gramene database in 2010: Updates and extensions
Youens-Clark K,
Buckler E,
Casstevens T,
Chen C,
DeClerck G,
Derwent P,
Dharmawardhana P,
Jaiswal P,
Kersey P,
Karthikeyan AS,
Lu J,
McCouch SR,
Ren L,
Spooner W,
Stein JC,
Thomason J,
Wei S,
Ware DH

Nucleic Acids Research
  39 (0): Jan 2011   PMCID: PMC3013721
[Abstract]
[DOI] [Full Text] [PDF]

Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila
Haase AD,
Fenoglio S,
Muerdter F,
Guzzardo PM,
Czech B,
Pappin DJ,
Chen C,
Gordon A,
Hannon GJ

Genes Dev
  24 (22): 2499-504; Oct 21 2010   PMCID: PMC2975926
[Abstract]
[DOI] [Full Text] [PDF]

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation
Fabian MR,
Mathonnet G,
Sundermeier T,
Mathys H,
Zipprich JT,
Svitkin YV,
Rivas F,
Jinek M,
Wohlschlegel J,
Doudna JA,
Chen CA,
Shyu A,
Yates Iii JR,
Hannon GJ,
Filipowicz W,
Duchaine TF,
Sonenberg N

Molecular Cell
  35 (6): 868-880 ; Sep 24 2009   PMCID: PMC2803087
[Abstract]
[DOI] [Full Text] [PDF]

Co-expression of Argonaute2 Enhances Short Hairpin RNA-induced RNA Interference in Xenopus CNS Neurons In Vivo
Chen CM,
Chiu SL,
Shen W,
Cline HT

Frontiers in Neuroscience
  3 (0): 63; 2009   PMCID: PMC2858607
[Abstract]
[DOI] [Full Text] [PDF]

The ARF Tumor Suppressor Can Promote the Progression of Some Tumors
Humbey O,
Pimkina J,
Zilfou JT,
Jarnik M,
Dominguez-Brauer C,
Burgess DJ,
Eischen CM,
Murphy ME

Cancer Res
  68 (23): 9608-9613; Dec 1 2008   PMCID: PMC2637809
[Abstract]
[DOI] [Full Text] [PDF]

Recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes
Mefford HC,
Sharp AJ,
Baker C,
Itsara A,
Jiang Z,
Buysse K,
Huang S,
Maloney VK,
Crolla JA,
Baralle D,
Collins A,
Mercer C,
Norga K,
de Ravel T,
Devriendt K,
Bongers EM,
de Leeuw N,
Reardon W,
Gimelli S,
Bena F,
Hennekam RC,
Male A,
Gaunt L,
Clayton-Smith J,
Simonic I,
Park SM,
Mehta SG,
Nik-Zainal S,
Woods CG,
Firth HV,
Parkin G,
Fichera M,
Reitano S,
Lo Giudice M,
Li KE,
Casuga I,
Broomer A,
Conrad B,
Schwerzmann M,
Raber L,
Gallati S,
Striano P,
Coppola A,
Tolmie JL,
Tobias ES,
Lilley C,
Armengol L,
Spysschaert Y,
Verloo P,
De Coene A,
Goossens L,
Mortier G,
Speleman F,
van Binsbergen E,
Nelen MR,
Hochstenbach R,
Poot M,
Gallagher L,
Gill M,
McClellan J,
King MC,
Regan R,
Skinner C,
Stevenson RE,
Antonarakis SE,
Chen C,
Estivill X,
Menten B,
Gimelli G,
Gribble S,
Schwartz S,
Sutcliffe JS,
Walsh T,
Knight SJ,
Sebat J,
Romano C,
Schwartz CE,
Veltman JA,
de Vries BB,
Vermeesch JR,
Barber JC,
Willatt L,
Tassabehji M,
Eichler EE

N Engl J Med
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[Abstract]
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Chiu SL,
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Neuron
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[Abstract]
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Nature
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[Abstract]
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Cell
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[Abstract]
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