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21 Article(s) on File
Page 1 of 1
A Computational Algorithm to Predict shRNA Potency
Knott SR,
Maceli AR,
Erard N,
Chang K,
Marran K,
Zhou X,
Gordon A,
El Demerdash O,
Wagenblast E,
Kim S,
Fellmann C,
Hannon GJ

Mol Cell
  (0): Nov 25 2014   Nlm
[Abstract]
[DOI] [Full Text]

A comparative encyclopedia of DNA elements in the mouse genome
Yue F,
Cheng Y,
Breschi A,
Vierstra J,
Wu W,
Ryba T,
Sandstrom R,
Ma Z,
Davis C,
Pope BD,
Shen Y,
Pervouchine DD,
Djebali S,
Thurman RE,
Kaul R,
Rynes E,
Kirilusha A,
Marinov GK,
Williams BA,
Trout D,
Amrhein H,
Fisher-Aylor K,
Antoshechkin I,
DeSalvo G,
See LH,
Fastuca M,
Drenkow J,
Zaleski C,
Dobin A,
Prieto P,
Lagarde J,
Bussotti G,
Tanzer A,
Denas O,
Li K,
Bender MA,
Zhang M,
Byron R,
Groudine MT,
McCleary D,
Pham L,
Ye Z,
Kuan S,
Edsall L,
Wu YC,
Rasmussen MD,
Bansal MS,
Kellis M,
Keller CA,
Morrissey CS,
Mishra T,
Jain D,
Dogan N,
Harris RS,
Cayting P,
Kawli T,
Boyle AP,
Euskirchen G,
Kundaje A,
Lin S,
Lin Y,
Jansen C,
Malladi VS,
Cline MS,
Erickson DT,
Kirkup VM,
Learned K,
Sloan CA,
Rosenbloom KR,
Lacerda de Sousa B,
Beal K,
Pignatelli M,
Flicek P,
Lian J,
Kahveci T,
Lee D,
Kent WJ,
Ramalho Santos M,
Herrero J,
Notredame C,
Johnson A,
Vong S,
Lee K,
Bates D,
Neri F,
Diegel M,
Canfield T,
Sabo PJ,
Wilken MS,
Reh TA,
Giste E,
Shafer A,
Kutyavin T,
Haugen E,
Dunn D,
Reynolds AP,
Neph S,
Humbert R,
Hansen RS,
De Bruijn M,
Selleri L,
Rudensky A,
Josefowicz S,
Samstein R,
Eichler EE,
Orkin SH,
Levasseur D,
Papayannopoulou T,
Chang KH,
Skoultchi A,
Gosh S,
Disteche C,
Treuting P,
Wang Y,
Weiss MJ,
Blobel GA,
Cao X,
Zhong S,
Wang T,
Good PJ,
Lowdon RF,
Adams LB,
Zhou XQ,
Pazin MJ,
Feingold EA,
Wold B,
Taylor J,
Mortazavi A,
Weissman SM,
Stamatoyannopoulos JA,
Snyder MP,
Guigo R,
Gingeras TR,
Gilbert DM,
Hardison RC,
Beer MA,
Ren B

Nature
  515 (7527): 355-64; Nov 20 2014   Nlm
[Abstract]
[DOI] [Full Text]

A Genomic-Scale Artificial MicroRNA Library as a Tool to Investigate the Functionally Redundant Gene Space in Arabidopsis
Hauser F,
Chen WX,
Deinlein U,
Chang K,
Ossowski S,
Fitz J,
Hannon GJ,
Schroeder JI

Plant Cell
  25 (8): 2848-2863; Aug 1 2013   NLM
[Abstract]
[DOI] [Full Text]

Modulators of Prostate Cancer Cell Proliferation and Viability Identified by Short-Hairpin RNA Library Screening
Dahlman KB,
Parker JS,
Shamu T,
Hieronymus H,
Chapinski C,
Carver B,
Chang K,
Hannon GJ,
Sawyers CL

PLoS ONE
  7 (4): Apr 11 2012  
[Abstract]
[DOI] [Full Text]

Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1)
Liu-Sullivan N,
Zhang J,
Bakleh A,
Marchica J,
Li J,
Siolas D,
Laquerre S,
Degenhardt YY,
Wooster R,
Chang K,
Hannon GJ,
Powers S

Oncotarget
  2 (12): 1254-64; Dec 2011   Nlm
[Abstract]
[DOI] [Full Text]

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann C,
Zuber J,
McJunkin K,
Chang K,
Malone CD,
Dickins R,
Xu Q,
Hengartner M,
Elledge SJ,
Hannon GJ,
Lowe SW

Molecular Cell
  41 (6): 733-746; Mar 18 2011   Array
[Abstract]
[DOI]

FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR
Bivona TG,
Hieronymus H,
Parker J,
Chang K,
Taron M,
Rosell R,
Moonsamy P,
Dahlman K,
Miller VA,
Costa C,
Hannon GJ,
Sawyers CL

Nature
  471 (7339): 523-526; Mar 2011   ISI
[Abstract]
[DOI]

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
Mavrakis KJ,
Wolfe AL,
Oricchio E,
Palomero T,
de Keersmaecker K,
McJunkin K,
Zuber J,
James T,
Chang K,
Khan AA,
Leslie CS,
Parker JS,
Paddison PJ,
Tam W,
Ferrando A,
Wendel HG

Nature Cell Biology
  12 (4): 372-U159; Apr 2010   PMCID: PMC2989719
[Abstract]
[DOI] [Full Text] [PDF]

DNA Sudoku - harnessing high-throughput sequencing for multiplexed specimen analysis
Erlich Y,
Chang K,
Gordon A,
Ronen R,
Navon O,
Rooks M,
Hannon GJ

Genome Res
  19 (7): 1243-1253 ; Jul 2009   PMCID: PMC2704425
[Abstract]
[DOI] [Full Text] [PDF]

Profiling essential genes in human mammary cells by multiplex RNAi screening
Silva JM,
Marran K,
Parker JS,
Silva J,
Golding M,
Schlabach MR,
Elledge SJ,
Hannon GJ,
Chang K

Science
  319 (5863): 617-20; Feb 1 2008   PMC2981870
[Abstract]
[DOI] [Full Text] [PDF]

Cancer proliferation gene discovery through functional Genomics
Schlabach MR,
Luo J,
Solimini NL,
Hu G,
Xu QK,
Li MZ,
Zhao ZM,
Smogorzewska A,
Sowa ME,
Ang XL,
Westbrook TF,
Liang AC,
Chang K,
Hackett JA,
Harper JW,
Hannon GJ,
Elledge SJ

Science
  319 (5863): 620-624; Feb 2008   PMC2981870
[Abstract]
[DOI] [Full Text] [PDF]

Lessons from Nature: microRNA-based shRNA libraries
Chang K,
Elledge SJ,
Hannon GJ

Nat Methods
  3 (9): 707-14; Sep 2006  
[Abstract]
[DOI] [Full Text] [PDF]

Second-generation shRNA libraries covering the mouse and human genomes
Silva JM,
Li MZ,
Chang K,
Ge W,
Golding MC,
Rickles RJ,
Siolas D,
Hu G,
Paddison PJ,
Schlabach MR,
Sheth N,
Bradshaw J,
Burchard J,
Kulkarni A,
Cavet G,
Sachidanandam R,
McCombie WR,
Cleary MA,
Elledge SJ,
Hannon GJ

Nat Genet
  37 (11): 1281-8; Nov 2005  
[Abstract]
[DOI] [Full Text]

Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis
Cleary MA,
Kilian K,
Wang Y,
Bradshaw J,
Cavet G,
Ge W,
Kulkarni A,
Paddison PJ,
Chang K,
Sheth N,
Leproust E,
Coffey EM,
Burchard J,
McCombie WR,
Linsley P,
Hannon GJ

Nat Methods
  1 (3): 241-8; Dec 2004  
[Abstract]
[Full Text]

RNA-interference-based functional genomics in mammalian cells: reverse genetics coming of age
Silva J,
Chang K,
Hannon GJ,
Rivas FV

Oncogene
  23 (51): 8401-9; Nov 1 2004  
[Abstract]
[DOI] [Full Text] [PDF]

Cloning of short hairpin RNAs for gene knockdown in mammalian cells
Paddison PJ,
Cleary M,
Silva JM,
Chang K,
Sheth N,
Sachidanandam R,
Hannon GJ

Nat Methods
  1 (2): 163-7; Nov 2004  
[DOI] [Full Text]

A resource for large-scale RNA-interference-based screens in mammals
Paddison PJ,
Silva JM,
Conklin DS,
Schlabach M,
Li M,
Aruleba S,
Balija V,
OShaughnessy A,
Gnoj L,
Scobie K,
Chang K,
Westbrook T,
Cleary M,
Sachidanandam R,
McCombie WR,
Elledge SJ,
Hannon GJ

Nature
  428 (6981): 427-31; Mar 25 2004  
[Abstract]
[DOI] [Full Text]

Gramene, a tool for grass Genomics
Ware DH,
Jaiswal PJ,
Ni JJ,
Yap I,
Pan XK,
Clark KY,
Teytelman L,
Schmidt SC,
Zhao W,
Chang K,
Cartinhour S,
Stein LD,
McCouch SR

Plant Physiology
  130 (4): 1606-1613; Dec 2002  
[Abstract]
[DOI] [Full Text]

Gramene: development and integration of trait and gene ontologies for rice
Jaiswal P,
Ware D,
Ni JJ,
Chang K,
Zhao W,
Schmidt S,
Pan XK,
Clark K,
Teytelman L,
Cartinhour S,
Stein L,
McCouch S

Comparative and Functional Genomics
  3 (2): 132-136; Apr 2002  
[Full Text]

Gramene: a resource for comparative grass genomics
Ware D,
Jaiswal P,
Ni JJ,
Pan XK,
Chang K,
Clark K,
Teytelman L,
Schmidt S,
Zhao W,
Cartinhour S,
McCouch S,
Stein L

Nucleic Acids Research
  30 (1): 103-105; Jan 2002  
[Full Text]

Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor
Stolarov J,
Chang K,
Reiner A,
Rodgers L,
Hannon GJ,
Wigler MH,
Mittal V

Proceedings of the National Academy of Sciences of the United States of America
  98 (23): 13043-13048; Nov 2001  
[Abstract]
[DOI] [Full Text]


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